| abstract |
Manufacturing methods, the pharmaceutical compositions that contain them and methods to use them especially to treat schizophrenia. Claim 1: A compound according to formula 1 wherein R1 is selected from C1-3alkyl or halogen; R2 is selected from C1-3 alkyl, C1-3 haloalkyl or C3-6 cycloalkyl; R3 and R4 in each occurrence are independently selected from hydrogen, C1-3 alkyl, C1-3 hydroxyalkyl, C3-6 carbocyclyl, heterocyclyl or heteroaryl, or R3 and R4 in combination with the nitrogen to which they are attached form a half c¡ Click on morpholino, pyrrolidinyl or piperazinyl. |