abstract |
A crystalline form of 6- [4S) -2-methyl-4- (naphthyl) -1,2,3,4-tetrahydroisoquinolin-7-i] pyridazin-3-amine. It also refers to pharmaceutical compositions comprising the crystalline form, as well as to methods for using a crystalline form in the treatment of depression and other conditions and procedures for obtaining such a crystalline form. Claim 2: The N-1 form characterized by the following unit cell meters: cell dimensions: a = 8.4299 (4) L, b = 6.0698 (3) L, c = 19.0689 (12) L, alpha = 90ø, beta = 100,169 (2) ø, gamma = 90ø Monoclonal space group, P21, Volume: 960.39 (9) L3 Z, Calculated density 2, 1,267 g / cm3 in which the measurement of the crystalline form mentioned is made at a temperature e between about 20 ° C and about 25 ° C. |