| abstract |
This refers to carbamoyl oxime derivatives of formula 1, the processes for their preparation and the pharmaceutical compositions containing them, for the treatment of neurological disorders, such as neuropathic pain and anxiety. Claim 1: A compound having the general formula (1) in which R1 and R2 are, independently, H, alkyl, aryl, arylalkyl, alkoxyaryl or haloaryl; or R1 and R2 taken together with the nitrogen atom to which they are attached, form a heterocycle; G is phenylene or thienylene; A is phenyl, thienyl, cyclohexyl, pyrrolyl or pyridyl; each of them is optionally substituted once or twice with aminocarbonyl or alkyl; their tautomers, their geometric isomers, their optically active forms, such as enantiomers, diastereoisomers and their racemate forms, as well as the pharmaceutically acceptable salts thereof; with the proviso that when A is cyclohexyl, R1 cannot be 4-Cl-phenyl and 3,4-dichlorophenyl, if R2 is H. |