http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-070993-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| filingDate | 2009-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dcda1224e820ef9f0345fe53f8110bd0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72ab985c0dba63d4ed6dcfdca8635053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a8cba428234ef71712740d152662e39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f8c1e0a566cefa89054b051c2f64a36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97b84e047c432bb6f65188db21825854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc2d3364e1db9df102f5ad8c900b721a |
| publicationDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-070993-A1 |
| titleOfInvention | POLISUSTITUTED DERIVATIVES OF 2-ARIL-6-PHENYL-IMIDAZO [1,2-A] PIRIDINES, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM, PROCESS OF PREPARATION OF THE SAME, INTERMEDIARIES OF SYNTHESIS AND USE OF THE SAME IN THE TREATMENT OR PREVENTION OF PREVENTION NURR-1 NUCLEAR RECEIVERS IMPLICATE, SUCH AS |
| abstract | Claim 1: Compounds of the formula (1) in which R 1 represents a phenyl group or a naphthyl group, these two groups being optionally substituted with one or more atoms or groups independently selected from each other among the following atoms or groups : halogen, C1-10 alkyl, C1-10 haloalkyl, C1-10 alkoxy, C1-10 haloalkoxy, C1-10 thioalkyl, -S (O) C1-10 alkyl, -S (O) 2-C1-10 alkyl, hydroxyl, cyano, nitro, C1-10 hydroxyalkylene, NRaRb-C1-10 alkylene, C1-10 alkoxy-C1-10 alkylene-oxy, NRaRb, CONRaRb, SO2NRaRb, NRcCORd, OC (O) NRaRb, OCO-C1-10 alkyl , NRcC (O) ORe, NRcSO2Re, C1-10 aryl-alkylene, monocyclic aryl or heteroaryl, the aryl or monocyclic heteroaryl being optionally substituted with one or more substituents chosen from a halogen, a C1-10 alkyl group, halo-alkyl C1-10, C1-10 alkoxy, halo-10-10 alkoxy, NRaRb, hydroxyl, oxo, nitro, cyano or OCO-C1-10 alkyl; X represents 1 to 4 identical or different substituents from one another, chosen from a hydrogen, a halogen, C 1-10 alkyl, C 1-10 alkoxy, NRaRb, cyano, nitro, the C 1-10 alkyl being optionally substituted with one or several groups chosen from a halogen, C1-10 alkoxy, halo-10-10 alkoxy, NRaRb or hydroxyl; R represents in position 3, 5, 7 or 8 of the imidazo [1,2-a] pyridine of 1 to 4 identical or different substituents from one another, chosen from a halogen, C1-10 alkyl, halo-C1-alkyl 10, C1-10 alkoxy; R2 and R3 represent, independently of one another, a hydrogen atom, a C1-10 alkyl group, optionally substituted with an Rf group; an aryl group, optionally substituted with one or more substituents chosen from a halogen, a C1-10 alkyl group, halo C1-10 alkyl, C1-10 alkoxy, halo C1-10 alkoxy, NRaRb, hydroxyl, nitro or cyano; R2 and X can form together with the carbon atoms to which a carbon cycle of 5 to 7 carbon atoms is attached; R4 represents: a hydrogen atom, a C1-10 alkyl group, optionally substituted with an Rf group; an aryl group, optionally substituted with one or more substituents chosen from a halogen, a C1-10 alkyl group, halo C1-10 alkyl, C1-10 alkoxy, halo C1-10 alkoxy, NRaRb, hydroxyl, nitro, cyano, C1-10 alkyl- (CO) -, CONRaRb, NRcCORd, OC (O) NRaRb, OCO-C1-10 alkyl, NRcC (O) ORe or aryl, the aryl being optionally substituted with one or more substituents chosen from a halogen, a C1-10 alkyl group, halo C1-10 alkyl, C1-10 alkoxy, halo C1-10 alkoxy, NRaRb, hydroxyl, nitro or cyano; Ra and Rb independently represent one another, a hydrogen atom or a C1-10 alkyl, aryl-C1-10 alkylene or aryl group; or Ra and Rb together, with the nitrogen atom that carries them, an azetidine, pyrrolidine, piperidine, azepine, morpholine, thiomorpholine, piperazine, homopiperazine group, this group being eventually substituted with a C1-10 alkyl, aryl or aryl group -C1-10 alkylene; Rc and Rd represent, independently of one another, a hydrogen atom or a C1-10 alkyl group, aryl-C1-10 alkylene, aryl; or Rc and Rd together form a C2-5 alkylene group; Re represents a C1-10 alkyl, C1-10 aryl alkylene, aryl group; or Rc and Re together form a C2-5 alkylene group; Rf represents a halogen atom, a C1-10 alkoxy group, C1-10 haloalkoxy, hydroxy, cyano, NRaRb, C (O) NRaRb, NRcCORd, OC (O) NRaRb, OCO-C1-10 alkyl, NRcCOORe, SO2NRaRb, NRcSO2Re, aryl-C1-10 alkylene, aryl, the aryl being optionally substituted with one or more substituents chosen from a halogen, a C1-10 alkyl group, halo C1-10 alkyl, C1-10 alkoxy, haloalkoxy C1-10, NRaRb, hydroxyl, nitro, cyano or OCO-C1-10 alkyl; in the form of base or salt of acid addition. |
| priorityDate | 2008-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.