http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-070982-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_981a37900e6991fb373304ed2ba5a703 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D411-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 |
| filingDate | 2009-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-070982-A1 |
| titleOfInvention | DIAMINOPIRIMIDINS; ITS USE AS PHYTOSANITARY AGENTS; AGENTS TO COMBAT ANIMAL PESTS AND / OR DAMIN FUNGES; PROCEDURE FOR COMBATING SUCH PESTS AND PROCEDURE FOR THE PREPARATION OF THE COMPOUND |
| abstract | Claim 1: Use of compounds of formula (1) as phytosanitary agents, wherein the symbols have the following meanings, X1 is nitrogen or CR3; X2 is nitrogen or CR4; wherein X1 and X2 do not simultaneously represent nitrogen, R1 and R5 are independently of each other hydrogen, C1-4 alkyl, C1-4 alkoxy or Hal, R2 to R4 are independently of each other hydrogen, halogen, cyano, nitro, a cycle 3 to 8 members, unsubstituted or substituted, saturated or unsaturated, which may contain none or up to four heteroatoms selected from N, O and S, where two oxygen atoms are not adjacent, OR12, O (CH2) mOR12; O (CH2) mN (R12) 2, O [C (R12) 2] mOR12, O [C (R12) 2] mN (R12) 2, OSO2N (R12) 2, OCON (R12) 2, OCOR13, SF5, SR12, SOR12, SO2R12, SON (R12) 2, SO2N (R12) 2, C = OR12, CH = NOR12, CR13 = NOR12, COCl, CON (R12) 2, COOR12, COO (CH2) mOR12, CO (CH2) mCN, NR12COR12, NR12COOR13, NR12 (C = S) OR13, N (R12) 2, NR12SO2R13, NR12SOR13, C (R12) 2OR12, [C (R12) 2] mCN, (CH2) mC (R12) 2OR12, (CH2 ) mOR12, (CH2) mSR12, [C (R12) 2] mSR12, (CH2) mSOR12, (CH2) mSO2R12, (CH2) mSON (R12) 2, (CH2) mSO2N (R12) 2, (CH2) mN ( R12) 2, [C (R12) 2] mN (R12) 2, (CH2) mCOOR12, (CH2) mCOR12, [C (R12) 2] mOR12, [C (R12) 2] mCOR12, [C (R12) 2] mCON (R12) 2, (CH2) mNR12COR12, (CH2) mNR12COOR13, [C (R12) 2] mNR12COR12, [C (R12) 2] mNR12COOR13, [C (R12) 2] mNR12OR12, C1-8 alkyl, C2-6 alkenyl, C1-8 haloalkyl unsubstituted or substituted; with m = 1-4 where additionally or independently of these every two adjacent residues R2, R3 or R4, if necessary by R12 or R13, they can together form a 3 to 7 member cycle, unsubstituted or substituted, saturated or unsaturated , which may contain none or up to four heteroatoms, selected from N, O and S, where two oxygen atoms are not adjacent. wherein the substituents are independently selected from each other of hydrogen, fluorine, chlorine or bromine, C1-4 alkyl, C1-4 alkoxy, hydroxy, oxo, C1-4 haloalkyl, or cyano, R6 is hydrogen, C1-2 alkyl, C1-4 alkoxy-C1-4 alkyl, trialkyl C1-4-silyl, trialkyl C1-4-silyl ethyl, dialkyl C1-4-monophenylsilyl, formyl, C1-4alkylcarbonyl, C1-4alkoxy-C1-alkyl 4-carbonyl, C3-6-oxy-carbonyl alkenyl, C3-6-cycloalkyl, C1-4 haloalkoxy-C1-4-alkylcarbonyl, C1-4-alkyl haloalkyl, C1-4-alkoxycarbonyl, C1-4 haloalkoxy -carbonyl, benzyloxycarbonyl, unsubstituted or substituted benzyl, unsubstituted or substituted C2-6 alkenyl, unsubstituted or substituted C2-6 alkynyl, C1-2-sulfinyl alkyl or C1-2-sulfonyl alkyl, wherein the substituents are independently selected from each other hydrogen, fluorine, chlorine or bromine, C1-4 alkyl, C1-4 alkoxy, hydroxy, C1-4 haloalkyl, or cyano, R7 is hydrogen, C1-3 alkyl, cyano or C1-3 haloalkyl, R8 is chlorine, bromine, and odo, cyano, methyl, CF3, CCI3, CFH2 or CF2H, R9 is hydrogen, C1-2 alkyl, C1-4 alkoxy-C1-4 alkyl, trialkyl C1-6-silyl, trialkyl C1-4-silyl ethyl, dialkyl C1-4-mono-phenyl-silyl, C1-4 alkylcarbonyl, haloC 1-4 alkylcarbonyl, C1-4 alkoxycarbonyl, unsubstituted or substituted benzyl, unsubstituted or substituted C2-6 alkenyl, C2-6 alkynyl unsubstituted or substituted, C1-6-sulfinyl alkyl, C1-6-sulfonyl alkyl, halo- C1-6-sulfinyl or haloalkyl C1-6-sulfonyl, wherein the substituents are independently selected from each other from fluorine, chlorine and / or bromine, cyano, hydroxy, methoxy, CF3; R10 is hydrogen, methyl, trifluoromethyl, nitrile, phenyl, meta-chlorophenyl, meta-fluorophenyl, para-chlorophenyl, para-fluorophenyl, benzyl, meta-chlorobenzyl, COOH, COOMe or COOEt, R11a is hydrogen, phenyl, para-methoxyphenyl or COOMe; R11b is hydrogen, fluorine, phenyl, para-methoxyphenyl, COOH or COOEt, R11c is hydrogen or fluorine, where only one of the residues R10, R11a, R11b or R11c is always different from hydrogen, or and R11b and R11c simultaneously represent fluorine; R12 is the same or different, hydrogen, C1-6 alkyl, C1-6 haloalkyl, unsubstituted or substituted C3-6 cycloalkyl, C1-4 trialkyl silyl, unsubstituted or substituted C2-4 alkenyl, unsubstituted C2-4 alkynyl or substituted, unsubstituted or substituted phenyl, C1-4 alkoxy-C1-4 alkyl, unsubstituted or substituted benzyl or a 3- to 7-membered, unsubstituted or substituted, saturated or unsaturated cycle, which may contain none or up to four selected heteroatoms of N, O and S, where two oxygen atoms are not adjacent or in the case that two R12 moieties are attached to a nitrogen atom, two R12 moieties can form a 3 to 7 membered cycle, unsubstituted or substituted, saturated or unsaturated, which may contain up to four additional heteroatoms, selected from N, O and S, where two oxygen atoms are not adjacent, or in the case that two R12 residues are present adjacent to the NR12COR12, NR12SOR12, NR12SO2R12 cluster, NR12SONR12, NR12SO2NR12, two rest s R12 can form a 3 to 7-member cycle, unsubstituted or substituted, saturated or unsaturated, which can contain up to four additional heteroatoms, selected from N, O and S, where two oxygen atoms are not adjacent, R13 is the same or different, C1-8 alkyl, C1-8 haloalkyl, C1-4 trialkyl-silyl, unsubstituted or substituted C2-6 alkenyl, unsubstituted or substituted C2-6 alkynyl, unsubstituted or substituted C3-6 cycloalkyl, unsubstituted aryl or substituted, C1-4 alkoxy-C1-4 alkyl, unsubstituted or substituted benzyl, or a 3 to 7 membered, unsubstituted or substituted, saturated or unsaturated cycle, which may contain none or up to four heteroatoms selected from N, O and S, where two oxygen atoms are not adjacent, where two R13 can form a 3- to 7-membered, unsubstituted or substituted, saturated or unsaturated cycle, which can contain up to four additional heteroatoms selected from N, O and S , where two oxygen atoms are not adjacent ntes, and where possible substituents are selected from the following list: fluorine, chlorine, bromine, iodine, cyano, nitro, CF3, CFH2, CF2H, C2F5, CCI3, hydroxy, OMe, OEt, OPr, OisoPr, OBu, OsecBu, OisoBu, OtercBu, O (CH2) 2OCH3, O (CH2) 3OCH3, O-cyclopentyl, O-phenyl, OCF3, OCF2H, OCF2CF3, OCF2CF2H, SH, SMe, SEt, SCF3, SCF2H, Sph, SCF5, SO2Me, SO2C, SO2C SOMe, SOEt, CO2H, CO2CH3, CO2Et, CO2Pr, CO2isoPr, CO2tercBu, COMe, COCF3, NH2, NHMe, NMe2, NHEt, NEt2, NHpr, NHisoPr, NHnBu, NHtercBu, NHisoBu, NHsecBu, cyclopropylamino, formyl, CH, CH2COCH3, CH2OMe, (CH2) 2OMe, (CH2) 3OMe, CH2OH, CH2SMe, (CH2) 2SMe, methyl, ethyl, propyl, 1-methyltethyl, butyl, 1-methyl-propyl, 2-methylpropyl, 1,1-dimethyl ethyl , cyclopropyl, 1-methoxycyclopropyl, 1-chlorocyclopropyl, cyclobutyl, 3-dimethylbutyl, cyclopentyl, cyclohexyl, cyclohexylmethyl, neopentyl, prop-2-en-1-yl, 1-methylprop-2-en-1-yl, but-3 -en-1-yl, trimethylsilyl methyl, cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl, phenyl, benzyl, - CH2CH = CH2, -CH (CH3) CH = CH2, -CH2C ::: CH, as well as salts of agrochemical activity thereof. Claim 4: Compounds of formula (2), wherein the symbols have the following meanings: R8a represents chlorine, iodine, CFH2, CF2H, CCI3, cyano or Me and X1, X2, R1 to R7, R1A, R9 to R13 have the meaning according to claim 1, as well as salts of agrochemical activity of these compounds. Claim 5: Compounds of formula (3), wherein the symbols have the following meanings: R8b represents CF3 and X1, X2, R1 to R7, R1A, R9, R10, R11a, b, c, R12 and R13 have the meanings according to claim 1, as well as salts of agrochemical activity of these compounds, with the exception of cases in which in the following subunit of general formula (2) X1 represents CR3 and X2 represents CR4 and either R2 and R3 or R3 and R4 together with the phenyl ring they form a moiety (1H-2-hydroxyindole-6-yl), (1H-2-hydroxyindole-7-yl) or (1H-3,4-dihydro-2-oxoquinolin-7-yl); or R3 is equal to CON (R12) 2 and both R12 moieties together with the nitrogen atom to which they are attached form a 4-methyl-1,4-piperazinyl moiety. Claim 6: Compounds of formula (4), wherein the symbols have the following meanings: R8c represents Br and X1, X2, R6, R7, R1A, R9, R10, R11a, b, c, R12 and R13 have the meanings according to claim 1, as well as salts of agrochemical activity of these compounds, with the exception of the following cases: either X1 represents CR3 and R2 and R3 form in the following subunit of general formula (4) one (1H-indazol-6-yl ) amine, or X1 represents CR3 and X2 represents CR4 and R4 and R3 form in the above subunit of general formula (4) also a (1 H-indazol-6-yl) amine. |
| priorityDate | 2008-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.