http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-070020-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 |
| filingDate | 2008-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_427556bd36ddf3c314f8888eebb7ef81 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f7920b13c87bcdc8242fc19bdf4358b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6621beaadf0b75434175432188d2c17a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d78e03cc1e994a21bd7dace1921ad8ff |
| publicationDate | 2010-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-070020-A1 |
| titleOfInvention | USE OF MGLUR5 ANTAGONISTS FOR THE TREATMENT OF GERD, PHARMACEUTICAL COMPOSITION AND TREATMENT METHOD |
| abstract | Claim 1: Use of a compound of the general formula (1) wherein one of A or E is N and the other is C; R1 is halogen; R2 is C1-6 alkyl; R3 is phenyl, pyridinyl, pyrazinyl, pyrimidinyl or pyridazinyl, which are optionally substituted by one, two or three substituents chosen from the group consisting of halogen, C1-6 alkyl, C1-6 alkoxy, C1-6 haloalkyl or C2-6 haloalkoxy ; R4 is CHF2, CF3, CH2OH or C1-6 alkyl; In the form of free base or acid addition salt they are very effective for the treatment, prevention and / or delay of the progress of gastro-esophageal reflux disorder (GERD). Claim 13: Pharmaceutical composition according to claim 12 further containing an anti-secreting agent, preferably chosen from the group consisting of proton pump inhibitors (PPI) and histamine H2 receptor antagonists. |
| priorityDate | 2007-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.