http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-069580-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0bf0928b608797b70bbc2b91c7e52e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-643 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D261-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N43-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-79 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D237-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-74 |
| filingDate | 2008-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2010-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-069580-A1 |
| titleOfInvention | PIRIDILMETIL-SULFONAMIDE COMPOUNDS, METHODS AND INTERMEDIARIES FOR THEIR PREPARATION, AN AGRICULTURAL COMPOSITION THAT UNDERSTANDS THEM, A METHOD TO COMBAT PHYTO-PATHOGENIC FUNGI THAT USES THEM, USE OF THESE COMPOUNDS FOR SUCH PURPOSE AND SEEDS. |
| abstract | Its use, to combat harmful phytopathogenic fungi and also with compositions and seeds comprising at least said compound. Methods for their preparation and synthesis intermediaries are also provided. Claim 1: Pyridylmethyl sulfonamide compounds characterized in that they have the formula (1) wherein: n indicates the amount of substituents R1 in the pyridine ring and n is 0, 1, 2, 3 or 4; m indicates the amount of substituents R3 in the phenyl ring and m is 0, 1, 2, 3 or 4; R1 is halogen, CN, NO2, OH, SH, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, C1-4 alkylthio, C1-4 haloalkylthio, C1-4 alkylsulfinyl, C1- haloalkylsulfinyl 4, C1-4 alkylsulfonyl, C1-4 haloalkylsulfonyl, amino, C1-4 alkylamino, di (C1-4 alkyl) amino, C1-4 alkoxy-C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C3 cycloalkyl -8 or C1-4 alkyl-C3-8 cycloalkyl; and / or two R1 radicals that bind adjacent carbon atoms of the pyridine ring can form, together with said carbon atoms, a fused benzene ring, a fused 5, 6 or 7 membered carbocycle fused saturated or partially unsaturated or a fused 5, 6 or 7-membered heterocycle containing 1, 2 or 3 heteroatoms selected from the group consisting of 2 nitrogen atoms, 1 oxygen atom and 1 sulfur atom as ring members, where it is possible for the fused ring bearing 1 or 2 radicals selected from the group consisting of halogen, C1-4 alkyl, halomethyl, C1-4 alkoxy or halomethoxy, where it is possible for n = 2, 3 or 4 that R1 is identical or different; R 2 is hydrogen, C 1-4 alkyl, C 1-4 haloalkyl, C 2-4 alkenyl, C 2-4 alkynyl, C 3-8 cycloalkyl, C 1-4 alkyl C 3-8 cycloalkyl or benzyl wherein the benzyl phenyl portion is unsubstituted or carries 1, 2, 3, 4 or 5 substituents selected from the group consisting of cyano, halogen, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, C1-4 alkoxycarbonyl and di- ( C1-4 alkyl) aminocarbonyl; R3 is halogen, CN, NO2, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy, or C1-4 haloalkoxy, where it is possible for m = 2, 3 or 4 that R3 is identical or different; Y is a divalent group selected from -O-, C1-4 alkanediyl, -O-CH2-, -CH2-O-, -C (NORn) -, -S-, S (= O) -, S (= O ) 2 and -N (Rn) -, wherein Rn is hydrogen or C1-4 alkyl and wherein the C1-4 alkanediyl moiety is unsubstituted or carries 1 or 2 substituents selected from the group consisting of oxo, cyano, halogen, C1-4 alkyl, C1-4 alkoxy, C1-4 haloalkyl and C1-4 haloalkoxy; Het is a 5- or 6-membered heteroaromatic radical, in which the atoms of the heteroaromatic radical ring member include, in addition to carbon atoms, 1, 2, 3 or 4 nitrogen atoms or 1 oxygen atom and 0, 1 or 2 nitrogen atoms or 1 sulfur atom and 0, 1 or 2 nitrogen atoms and wherein the heteroaromatic radical is unsubstituted or carries 1, 2, 3 or 4 identical or different Ra substituents, where two Ra radicals that are attached At atoms of adjacent ring members they can form a fused 5 or 6 membered carbocycle or heterocycle, wherein the fused carbocycle or heterocycle is unsubstituted or carries 1, 2, 3 or 4 identical or different Rb substituents; Ra is halogen, CN, NO2, C1-4 alkyl, C1-4 haloalkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 alkoxy, C1-4 haloalkoxy, C1-4 alkylthio, C1-4 haloalkyl, C1 alkylsulfinyl -4, C1-4 haloalkylsulfinyl, C1-4 alkylsulfonyl, C1-4 haloalkylsulfonyl, amino, C1-4 alkylamino, di (C1-4 alkyl) amino, C1-4 alkoxy-C1-4 alkyl, a C radical (= O ) R, wherein R is H, C 1-4 alkyl, C 1-4 haloalkyl, C 2-4 alkenyl, C 2-4 alkynyl, C 1-4 alkoxy, C 1-4 alkoxy-C 1-4 alkoxy, C 1-4 haloalkoxy, amino , C1-4 alkylamino or di (C1-4 alkyl) amino; a radical CR '(= NOR' '), wherein R' is H or C1-4 alkyl and R '' is C1-4 alkyl, C1-4 haloalkyl, C2-4 alkenyl, C2-4 alkynyl or C1- alkoxy 4-C 1-4 alkyl, phenyl, pyridinyl, pyrimidinyl, phenoxy or phenoxyalkyl, wherein the last five radicals mentioned are unsubstituted or carry 1, 2, 3 or 4 identical or different Rc substituents; Rb and Rc are independently selected from halogen, CN, NO2, OH, SH, C1-4 alkyl, C1-4 haloalkyl, C1-4 alkoxy and C1-4 haloalkoxy; and the N-oxides and salts acceptable in agriculture of the compounds of the formula (1). Claim 7: A process for preparing pyridylmethyl sulfonamide compounds of the formula (1) as defined in any one of claims 1 to 6, characterized in that it comprises reacting an aminomethylpyridine compound of the formula (2) wherein n, R1 and R2 are as defined in claim 1, under basic conditions with a sulfonic acid derivative of the formula (3) wherein Y, Het, m and R3 are as defined in claim 1 and L is a leaving group as halogen, hydroxy, azido, optionally substituted heteroaryl, optionally substituted heteroaryloxy or optionally substituted phenoxy, preferably chloro, fluoro, optionally substituted heteroaryl such as pyrazol-1-yl, imidazol-1-yl, 1,2,3-triazol-1 -yl and optionally substituted 1,2,4-triazol-1-yl, pentafluorophenoxy or hydroxybenzotriazoloxy. Claim 8: A process for preparing pyridylmethyl sulfonamide compounds of the formula (1) as defined in any of claims 1 to 6, characterized in that it comprises reacting a compound of the formula (4) wherein n and R 1 are as is defined in claim 1 and L 'is a leaving group such as methylsulfonyl, toluenesulfonyl or as defined for L in the formula (3) in claim 7, under basic conditions with the compound of formula (5) wherein Y, Het , m, R2 and R3 are as defined in claim 1. Claim 9: Compounds characterized in that they have the formula (2), wherein R2 is defined according to claim 1, n is 2 and R1 is in position 2 and 3 of the pyridine ring and where R1 in position 2 is different from R1 in position 3 and if one of the two R1 is CH3, the other R1 is not OCH3. Claim 10: Compounds characterized in that they have the formula (3), wherein R3, Y and Het are defined according to claim 1, L is halogen and m is 1, 2, 3 or 4. |
| priorityDate | 2007-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 60.