| abstract |
A process for its preparation, pharmaceutical compositions comprising the compounds. Claim 1: A compound of formula (1) wherein: X is a remainder of the group of formulas (2); Q is a remainder of the group of formulas (3); R¹ is hydrogen, C₁₋₃ alkyl, C₁₋₃ alkoxy, OR⁴ or NR⁴R⁵; R² is C₁₋₃ alkyl or cyclopropyl; R³ is hydrogen, methyl, halogen or cyano; R⁴ is hydrogen or C₁₋₃ alkyl; R⁵ is hydrogen or C₁₋₃ alkyl; And it is pyrrolidine, optionally fused with cyclopropyl; Z is a remainder of the group of formulas (4), where R⁶ is hydrogen, C₁₋₃ alkyl or C₁₋₃ alkoxy; R⁷ is hydrogen, C₁₋₃ alkyl or C₁₋₃ alkoxy; R⁸ is hydrogen, CONR⁹R¹⁰ or NR⁹R¹⁰; R⁹ is hydrogen or C₁₋₃ alkyl; R¹⁰ is hydrogen or C₁₋₃ alkyl; as well as pharmaceutically acceptable salts, hydrates, isoforms, tautomers and / or enantiomers thereof. |