| abstract |
Claim 1: Compounds of formula (1) (A) m À (B) n wherein A represents an angiotensin conversion enzyme inhibitor compound that carries at least one basic salifiable function, B represents a compound that leads to At least one salifiable acid function and at least one NO donor group, m represents the number of functions quoted from B and n represents the number of basic functions quoted from A, and it should be understood that the link (s) between A and B are ionic. Claim 2: Compounds of formula (1) according to claim 1, wherein A belongs to formula (2) in which: R1 represents a hydrogen atom or a linear or branched C1-6 alkyl group, R2 represents a group linear or branched C1-6 alkyl or aryl C1-6 alkyl in which the alkyl group is linear or branched, R3 represents a linear or branched C1-6 alkyl or C1-6 amino alkyl group in which the alkyl group is linear or branched , the remainder of formula (3) represents a mono- or bicyclic nitrogen system having 3 to 12 carbon atoms and having one or more supplementary heteroatoms selected from N, O and S, said system being optionally substituted by one or more groups selected from linear or branched C1-6 alkyl, linear or branched C1-6 alkoxy, oxo, carboxy, aryl, C3-8 cycloalkyl, heteroaryl, carboxy-C1-6 alkyl in which the alkyl group is linear or branched, hydroxy, It should be understood that when the nitrogen system ado is bicyclic, it can be fissioned, spirited or bridged. |