http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-066743-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-54 |
| filingDate | 2008-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d08aee0002fddf5f7b455ef58a46009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23e329789b9e2933b84ba30a2d02bc42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed8146c9bd729a6e19c02b9ad0560855 |
| publicationDate | 2009-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-066743-A1 |
| titleOfInvention | NON-NUCLEOSIDE INHIBITORS OF THE REVERSE TRANSCRIPT |
| abstract | These compounds inhibit HIV-1 reverse transcriptase and provide a method for the prevention and treatment of HIV-1 infections and treatment of AIDS and / or ARC. The present invention also relates to compositions containing compounds of formula I that are useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and / or ARC. Claim 1: A compound of the formula (1) wherein: A is (a) CHR3 = CHR2, (b) CH2R3CH2R2 or (c) CHR2; or (i) R1 is (2) and R2 is hydrogen, C1-3 alkyl, C1-3 haloalkyl, C2-6 alkenyl, or CH2ORc; and furthermore, if A is (a) or (b), R2 may also be halogen, NRaRb, CN or ORc; or (ii) R1 is C1-6 alkyl and R2 is (2); X1 is O or S; X2 is O, or, if A is (a), X2 is O or NRd; R3 is hydrogen or C1-3 alkyl; R4 is halogen, C1-6 alkyl, C3-6 cycloalkyl, C1-6 haloalkyl or C1-6 alkoxy; Ra and Rb are independently hydrogen, C1-3 alkyl or C1-6 acyl; Rc and Rd are independently hydrogen or C1-3 alkyl; Ar is phenyl substituted by 1-3 groups independently selected from halogen, cyano, C1-6 haloalkyl, C1-6 alkyl, C1-6 alkoxy and C3-6 cycloalkyl; n is an integer from 1 to 3; or its pharmaceutically acceptable salts. |
| priorityDate | 2007-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.