http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-066674-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C243-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6889 |
| filingDate | 2008-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b37ba74a61a8df3edb3407989e738e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54f1afb23cc715d45d1bc8cae49a6f75 |
| publicationDate | 2009-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-066674-A1 |
| titleOfInvention | METHODS TO PREPARE A HYRAZAC HYRAZIDE AND ACIL CHLORIDE, A COMPOSITE CONTAINING A HYDRAZIDE LINK, ACID HYDRAZIDE 3- METHYL-3 MERCAPTO-BUTANEOUS AND AN IMMUNOCATE OF A FAMILY MEMBER AS A CALIQUEL CARRIER |
| abstract | A method for preparing hydrazides from hydrazine and an acyl chloride comprising the steps of: (a) preparing a substantially stirred suspension and an inert solvent at low temperature; and (b) adding an acyl chloride continuously to said suspension. The method avoids or limits the production of unwanted bis-hydrazide by-products. The method is used to prepare 3-methyl-3-mercaptobutanoic acid hydrazide, a molecule used to bind calicheamycin to a monoclonal anti-body. |
| priorityDate | 2007-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.