http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-066460-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-096 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-451 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-22 |
| filingDate | 2008-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-066460-A2 |
| titleOfInvention | COMPOUNDS DERIVED FROM PHENYL-PIPERAZINE, PHENYL-PIPERIDINE AND PHENYL-TETRAHIDROPIRIDINE AS INHIBITORS OF THE REABSORTION OF SEROTONIN, A PHARMACEUTICAL COMPOSITION AND USE OF THE SAME FOR THE PREPARATION OF MEDICINES |
| abstract | Pharmaceutical composition and the use of such derivatives for the preparation of medicaments for the treatment of affective disorders, including depression, anxiety disorders that include general disorder and anxiety and panic disorder and obsessive compulsive disorder. Claim 1: A compound derived from phenyl-piperazine, phenyl-piperidine and phenyltetrahydropyridine represented by the general formula (1); in which Y is N, C or CH; X represents O or S; m is worth 1 or 2; p is worth 0,1, 2, 3, 4, 5, 6, 7 or 8; worth 0.1, 2, 3 or 4; s is worth 0, 1, 2, 3, 4 or 5; the dashed line represents an optional link; each of the R1, is selected, independently of the others, from the group represented by C1-6 alkyl, or two R1 attached to the same carbon atom can form a 3 to 6 membered spiro-fixed cycloalkyl; each of the R2 is selected, independently of the others, from the group represented by halogen, cyano, nitro, C1-6 alkyl / alkenyl / alkynyl, C1-6 alkyl / alkenyl / alkynyloxy, C1-6 alkyl / alkenyl / alkylsulfanyl, hydroxy, hydroxyalkyl / alkenyl / C1-6 alkynyl, haloalkyl / alkenyl / C1-6 alkynyl, haloalkyl / alkenyl / C1-6 alkyloxy, cycloalkyl / alkenyl / C3-8 alkynyl, cycloalkyl / alkenyl / C3-8 alkynyl / alkenyl / C1-6 alkynyl, acyl, C1-6 alkyl / alkenyl / alkyloxycarbonyl, C1-6 alkyl / alkenyl / alkylsulfonyl, or -NRxRy; -NRxCO-alkyl / alkenyl / C1-6 alkynyl; each of the R3, is selected, independently of the others, from the group represented by halogen, cyano, nitro, C1-6 alkyl / alkenyl / alkynyl, C1-6 alkyl / alkenyl / alkynyloxy, C1- alkyl / alkenyl / alkylsulfanyl 6, hydroxy, hydroxyalkyl / alkenyl / C1-6 alkynyl, haloalkyl / alkenyl / C1-6 alkynyl, haloalkyl / alkenyl / C1-6 alkyloxy, cycloalkenyl / C3-8 alkyl, cycloalkenyl / C3-8-a-alkyl / alkenyl / alkynyl -6, C1-6 alkyl / alkenyl / alkylsulfonyl, aryl, C1-6 alkyl / alkenyl / alkyloxycarbonyl, acyl, -NRxCO-alkyl / C1-6 alkenyl / alkynyl, -CONRxRy or NRxRy or, two R3 substituents together form a heterocycle fused to the phenyloselected ring from the group consisting of formulas (2) in which W is O or S; and R 'and Rö are hydrogen or C1-6 alkyl; or, two adjacent R3 substituents together form a fused heteroaromatic system containing 1, 2 or 3 heteroatoms, where each of the Rx and Ry is selected, independently of the others, from the group represented by hydrogen, alkyl / alkenyl / C1-alkynyl 6, C3-8 cycloalkyl / alkenyl, C3-8 cycloalkyl / alkenyl / C1-6 alkenyl / alkynyl, or aryl; or, Rx and Ry form together with the nitrogen atom to which they are attached, a ring of 3 to 7 members that optionally contain another heteroatom; or a pharmaceutically acceptable acid addition salt thereof. |
| priorityDate | 2001-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.