http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-066206-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65f6765a6f0387cfcb75bc6a09213161 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 |
| filingDate | 2008-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_713da73bdbdbbcbd588c9ae95164fb4f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50ddeffa92a3eb5bf0e0ef92cf71cfc5 |
| publicationDate | 2009-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-066206-A1 |
| titleOfInvention | PROCESS FOR SYNTHESIS OF SOLIFENACINE |
| abstract | Synthesis for the preparation of solifenacin and its acceptable salts for pharmaceutical use. Claim 1: A process for preparing solifenacin base of formula (1), or a salt thereof, characterized in that said process comprises: (i) reacting (3R) -3-quinuclidinol of formula (2), with 1,1 -carbonyl-di- (1,2,4-triazole) of formula (3), in an organic solvent to obtain a mixture, and (ii) combine the mixture of step (i) with (S) -1-phenyl- 1,2,3,4-tetrahydroisoquinoline of formula (4), in the presence of a base to obtain solifenacin base. |
| priorityDate | 2007-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.