http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-065125-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y203-01037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P5-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-02002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y603-02003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P9-00 |
| filingDate | 2008-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2009-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-065125-A1 |
| titleOfInvention | GENETICALLY MODIFIED HOSPED CELLS FOR INCREASED P450 ACTIVITY LEVELS AND METHODS OF THE SAME USE |
| abstract | The present application relates to genetically modified host cells that exhibit levels of modified activity of one or more gene products, so that when a cytochrome P450 enzyme is produced in genetically modified host cells, the modified activity levels of one or more Gene products provide improved production and / or activity of the cytochrome P450 enzyme. The present application provides methods for producing a cytochrome P450 enzyme in a host cell, in general, which involves culturing a genetically modified host cell subject in a suitable culture medium. The present application further provides methods for producing a product of a P450-dependent oxidation, in general, which involves culturing a subject genetically modified host cell, in a suitable culture medium. Claim 1: A genetically modified host cell, characterized in that said genetically modified host cell comprises a nucleic acid comprising a nucleotide sequence encoding a gene product related to oxidative stress, wherein the production of the stress-related gene product Oxidative provides increased production of an isoprenoid or isoprenoid precursor by the genetically modified host cell, compared to a control host cell not genetically modified with the nucleic acid. |
| priorityDate | 2007-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 252.