| abstract |
A process for preparing a pharmaceutical formulation comprising the steps of: (i) dissolving at least one dissolution improving agent in at least one aqueous diluent where the dissolution improving agent is urea, L-histidine, L-threonine, L -asparragine, L-serine, L-grutamine or mixtures thereof; (ii) adding at least one antineoplastic agent or a pharmaceutically acceptable salt thereof; a lyophilized powder comprising the pharmaceutical formulation, and articles of manufacture thereof. |