| abstract |
This provides compositions and methods related to antigen binding proteins that bind to the human glucagon receptor, including antibodies. In particular embodiments, the human, humanized and chimeric anti-human glucagon receptor antibodies and fragments and derivatives of those antibodies are provided in the disclosure. Likewise, antibodies competing with each other to bind to a specific site in the human glucagon receptor are disclosed. Nucleic acids encoding those antibodies and antibody fragments and derivatives, and methods for preparing and using those antibodies are also disclosed, including methods for treating and preventing type 2 diabetes by administering these antibodies to a patient in need of this treatment. |