http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-062796-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_132aa5ddba376cda52c2bedb26765245 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0202 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 |
| filingDate | 2007-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_948afa9fab2304586b4a091760b066e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d79b459d95cda7103d2904682c7f56a3 |
| publicationDate | 2008-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-062796-A1 |
| titleOfInvention | MARKING METHODS WITH RADIOACTIVE FLUOR |
| abstract | Radioactively labeled substituted benzene compounds for diagnostic imaging; methods for preparing these compounds, in particular, for preparing compounds that serve as precursors for 18F labeling, and the use of these 18F labeled compounds for diagnostic imaging. Claim 1: A compound characterized in that it has a general chemical formula (1), wherein one of -Y1, -Y2, -Y3, -Y4 and -Y5 is a first substituent (-G) that is selected from the group comprising -H , -F - Cl, -Br, -I, -NO, -NO2, -NR4COCF3, -NR4SO2CF3, -N (CF3) 2, - NHCSNHR4, -N (SO2R5) 2, -N (O) = NCONH2, - NR4CN, NHCSR5, -N ::: C, -N = C (CF3) 2, -N = NCF3, -N = NCN, -NR4COR4, -NR4COOR5, -OSO2CF3, -OSO2C6H5, -OCOR5, -ONO2, -OSO2R5 , -OC = CH2, - OCF2CF3, -OCOCF3, -OCN, -OCF3, -C ::: N, -C (NO2) 3, -COOR4, -CONR4R5, -C (S) NH2, -CH = NOR4, -CH2SO2R4, -COCF3, -CF3, -CF2ClCBr3, -CClF2, -CCl3, -CF2CF3, -C ::: CR4, -CH = NSO2CF3, CH2CF3, COR5, -CH = NOR5, -CH2CONH2, -CSNHR5, -CSNHR5, -CSNHR5 = NNHCSNH2, CH = NNHCONHNH2, - C ::: C-CF3, -CF = CFCF3, -CF2-CF2-CF3, -CR4 (CN) 2, -COCF2CF2CF3, -C (CF3) 3, -C (CN) 3, -CR4 = C (CN) 2, -1-pyrrile, -C (CN) = C (CN) 2, -C-pyridyl, -COC6H5, -COOC6H5, SOCF3, -SO2CF3, -SCF3, SO2CN, - SCOCF3, -SOR5, -S (OR5), SC ::: CR4, -SO2R5, -SSO2R5, -SR5, -SSR4, - SO2CF2CF3; -SCF2CF3, -S (CF3) = NSO2CF3, -SO2C6H5, -SO2N (R5) 2, SO2C (CF3) 3, SC (CF3), -SO (CF3) = NSO2CF3, -S (O) (= NH) CF3 , S (O) (= NH) R5, SC = CH2, -SCOR5, -SOC6H5, -P (O) C3F7, -PO (OR5) 2, -PO (N (R5) 2) 2, -P (N (R5) 2) 2, -P (O) R52 and -PO (OR5) 2, and electron subtraction groups, where the respective substituent may be in ortho position, for or goal with respect to group K (LG-O); at least one of -Y1, -Y2, -Y3, -Y4, and -Y5 is an additional substituent (-Q) that is independently selected from the group comprising -H, -CN, halogen, -CF3, -NO2, - COR5 and SO2R5, where the respective substituent may be in ortho, para or meta position with respect to the group K (LG-O), where R4 is H or a linear or branched C1-6 alkyl; R5 is H or a linear or branched C1-6 alkyl, where in addition, one of -Y1, -Y2, -Y3, -Y4 and -Y5 is -ABDP, where -ABD- is a bond or a separator, P is a addressing agent, and K is LG-O or W, where: LG is a leaving group, which can be displaced with an aromatic nucleophilic substitution reaction, and W is a fluorine isotope (F) and also any organic salt or acid or inorganic, hydrate, ester, amide, solvate and prodrugs thereof acceptable for pharmaceutical use. |
| priorityDate | 2007-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.