http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-061993-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_132aa5ddba376cda52c2bedb26765245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a910d33c239980f3a705e312c5bad6a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C215-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-16 |
| filingDate | 2007-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8263c826ed3d31e9fb3d99e099df816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_096c2d646fa6a4174ab4cfcb01ae4069 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88ac91eb52c1e88089acf318147abaf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9237e58d95702f09238d327ae6fcb08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf869a452072c37b8d67b29395e7072e |
| publicationDate | 2008-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-061993-A1 |
| titleOfInvention | BENCILAMINS, A PROCESS FOR ITS PRODUCTION AND ITS USE AS ANTI-INFLAMMATORY AGENTS |
| abstract | Processes for its production and its use as anti-inflammatory agents. Claim 1: Stereoisomers characterized in that they respond to the general formula (1) wherein R¹ and R² independently of one another, mean a hydrogen atom, a hydroxy group, a halogen atom, an optionally substituted C₁₋₁₀ alkyl group, a optionally substituted C₁₋₁₀ alkoxy group, a C₁₋₁₀ alkylthio group, a C₁₋₅ perfluoroalkyl group, a cyano group, a nitro group, or R¹ and R² together means a group selected from the groups -O- (CH₂) ₚ-O-, -O- (CH₂) ₚ-CH₂-, -O-CH = CH-, - (CH₂) ₚ₊₂-, -NH- (CH₂) ₚ₊₁, N (C₁₋₃ alkyl) - (CH₂) ₚ₊₁, and -NH-N = CH-, in which p = 1 or 2, and the oxygen atoms and / or carbon atoms and / or terminal nitrogen atoms bind to the atoms of directly adjacent ring carbon, or NR⁷R⁸, wherein R⁷ and R⁸, independently of each other, mean hydrogen, C₁₋₅ alkyl or (CO) -C₁₋₅ alkyl; R³ means a hydrogen atom, a hydroxy group, a halogen atom, a cyano group, an optionally substituted C₁₋₁₀ alkyl group, a C₁₋₁₀ alkoxy group, a C₁₋₁₀ alkylthio group, or a C₁₋₅ perfluoroalkyl group ; R⁴ means a monocyclic, or bicyclic, aromatic, partially aromatic, or non-aromatic ring system, which optionally contains 1-4 nitrogen atoms, 1-2 oxygen atoms and / or 1-2 sulfur atoms and is optionally substituted in one or more positions with a radical selected from the group carbonyl, halogen, hydroxy, or C₁₋₅ alkyl, which may optionally be substituted with 1-3 C₁₋₅ alkoxy groups and / or 1-3 COOR⁶ groups, C₁₋₅ alkoxy, C₁₋₅ alkylthio, C₁₋₅ perfluoroalkyl, cyano, nitro, or two substituents together form a group that is selected from the groups -O- (CH₂) ₚ-O-, -O- (CH₂) ₚ -CH₂-, -O-CH = CH-, - (CH₂) ₚ₊₂-, -NH- (CH₂) ₚ₊₁, -N (C₁₋₃ alkyl) - (CH₂) ₚ₊₁-, and - NH-N = CH-, in which p = 1 or 2, and the oxygen atoms and / or carbon atoms and / or terminal nitrogen atoms are attached to the directly adjacent ring carbon atoms, NR⁷R⁸, where R⁷ and R⁸, independently of one another, they may be hydrogen, C₁₋₅ alkyl or (CO) -C₁₋₅ alkyl (CO) NR¹¹R en², where R¹¹ and R independiente² independently of one another, mean hydrogen or a C₁₋₅ alkyl group, or a C₁₋₅-O- (CO) -C₁₋₅ alkyl group; R⁵ means a partially or completely fluorinated C₁₋₃ alkyl group; R⁶ means a group selected from C₁₋₁₀ alkyl, which may be optionally partially or fully halogenated, C₂₋₁₀ alkenyl, C₂₋₁₀ alkynyl, C₁₋₈ alkyl-C₃₋₇ cycloalkyl, C₂₋₈ alkenyl-C₃₋₇ cycloalkyl , C₁₋₈heterocyclyl alkyl, C₂₋₈heterocyclyl alkenyl, -R⁹, C₁₋₈-R⁹ alkyl, C₂₋₈-R⁹ alkenyl, C₂₋₈-R⁹ alkynyl, -CH₂-S-C₁₋₁₀ alkyl, -CH₂-S- R⁹, -CH₂-SO₂-R⁹, - (CH₂) ₙ-R⁹, -CH₂-SO₂-C₁₋₁₀ alkyl, - (CH₂) ₙ-CN, - (CH₂) ₙ-Hal, where Hal means F, Cl , or I, -CH₂-O-C₁₋₁₀ alkyl, - (CH₂) ₙ-NR⁷R⁸ wherein R⁷, R⁸ have the meaning indicated above, -CH₂-O-R⁹, with the exception of -CH₂-CH (CH₃) ₂, -CH = C (CH₃) ₂ or -CH₂-C (CH₃) = CH₂ where R⁹ means an aryl which can be optionally substituted with 1-3 alkyl, hydroxy, halogen, cyano or C₁₋₅ alkoxy group or a heteroaryl group in dond and the heteroaryl group may contain 1-3 heteroatoms which may optionally be substituted with 1-3 alkyl, hydroxy, halogen, cyano or C₁₋₅ alkoxy groups; n means an integer selected from 1, 2, 3, 4, 5. |
| priorityDate | 2006-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 60.