| abstract |
A compound that is the salt of toluenesulfonic acid of 4 - {[6-chloro-3 - ({[(2-chloro-3-fluorophenyl) amino] carbonyl} amino) -2-hydroxyphenyl] sulfonyl} -1-piperazine carboxylate of 1,1-dimethyl ethyl. Pharmaceutical composition that includes it. Use of said compound for the manufacture of a medicament useful for the treatment of a chemokine-mediated disease that binds to an IL-8 alpha or beta receptor, such as asthma, chronic obstructive pulmonary disease or respiratory failure syndrome in adults. Pharmaceutical combination of said compound and one or more additional therapeutic ingredients, such as a CXCR3 receptor antagonist or a CCR5 receptor antagonist. Method to synthesize said compound. |