http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-061181-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-396 |
| filingDate | 2007-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a4ad03dc5b577d87cdc616219a6c6c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed7ad7e3787c050530020845df895731 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2089fc305b612102144b63cf5f16e556 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d07e92f7443a7b3541bc65bb4fec8387 |
| publicationDate | 2008-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-061181-A1 |
| titleOfInvention | AZIRIDINIL-EPOTILONE COMPOUNDS |
| abstract | Claim 1: A compound characterized in that it has the Formula (1) or pharmaceutically acceptable salts thereof, wherein: K is -O-, -S-, or -NR7-; A is - (CR8R9) - (CH2) mZ- where Z is - (CHR10) -, -C (= O) -, -C (= O) -C (= O) -, -OC (= O) -, - N (R11) C (= O) -, -SO2-, or -N (R11) SO2-; B1 is hydroxyl or cyano, and R1 is hydrogen or B1 and R1 are taken together to form a double bond; R2, R3 and R5 are, independently, hydrogen, alkyl, substituted alkyl, aryl or substituted aryl; or R2 and R3 can be taken together with the carbon to which they bind to form an optionally substituted cycloalkyl; R4 is hydrogen, alkyl, alkenyl, substituted alkyl, substituted alkenyl, aryl, or substituted aryl; R6 is hydrogen, alkyl or substituted alkyl; R7, R8, R9, R10 and R11 are independently hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, heterocycloalkyl, substituted heterocycloalkyl, heteroaryl, or substituted heteroaryl; R12 is H, alkyl, substituted alkyl, or halogen; R13 is aryl, substituted aryl, heteroaryl or substituted heteroaryl; and m is 0 to 6. |
| priorityDate | 2006-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.