abstract |
Claim 1: A compound of formula (1) wherein R1 is hydrogen or fluoro; R2 is hydrogen, fluoro or C1-3 alkyl; R3 is C1-3 alkyl or cyclopropyl; X is (2) and Z is (3) where R4 is hydrogen, C1-3 alkyl, C1-3 haloalkyl, C1-3 alkoxy; C1-3 haloalkoxy; or halogen; R5 is hydrogen, C1-3 alkyl, C1-3 haloalkyl, C1-3 alkoxy; C1-3 haloalkoxy; or halogen; R6 is hydrogen, fluoro or C1-3 alkyl, as well as its salts acceptable for pharmaceutical use, hydrates, isoforms, tautomers and / or enantiomers. |