http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-060665-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6031 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6037 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55583 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-183 |
| filingDate | 2007-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2008-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-060665-A1 |
| titleOfInvention | FORMULATIONS THAT STABILIZE AND INHIBIT THE PRECIPITATION OF IMMUNOGENIC COMPOSITIONS |
| abstract | Claim 1: A formulation that stabilizes a polysaccharide-protein conjugate, the formulation comprising (1) a pH buffered saline solution, wherein the buffer has a pKa of approximately 3.5 to approximately 7.5, (ii) a surfactant and (iii) one or more polysaccharide protein conjugates. Claim 2: The formulation of claim 1, wherein the formulation of the polysaccharide-protein conjugate is comprised in a container selected from one or more of the group consisting of a bottle, bottle cap, bottle closure, closure of glass, rubber glass, plastic closure, a syringe, syringe cap, syringe plunger, a vial, beaker, graduated cylinder, fermenter, bioreactor, pipe, tube, bag, jar, blister, cartridge and disposable pen. Claim 3: The formulation of claim 1, in which the container is silicone. Claim 4: The formulation of claim 1, wherein the buffer is succinate at a final concentration of 1 mM to 10 mM and pH 5.8 to 6.0. Claim 5: The formulation of claim 1, wherein the surfactant is polysorbate 80. Claim 6: The formulation of claim 5, wherein the final concentration of polysorbate 80 in the formulation is at least 0.001% to 10 Polysorbate% 80 weight / volume of the formulation. Claim 7: The formulation of claim 1, wherein the polysaccharide-protein conjugate comprises one or more of the pneumococcal polysaccharides. Claim 8: The formulation of claim 1, which further comprises one or more meningococcal polysaccharides, one or more meningococcal antigenic proteins or a combination thereof. Claim 9: The formulation of claim 1, which further comprises one or more streptococcal polysaccharides, one or more streptococcal antigenic proteins or a combination thereof. |
| priorityDate | 2006-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.