http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-059917-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_938a6d7a15cbc93a74abe1953eb25d47 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D301-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0202 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-10 |
| filingDate | 2007-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a66a3bb7341011ffad54416f15eed25a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23a8ecdd42bb7886ef96624097a12c07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_696959e8cca8fe6057d0f8aafd3979fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dad2514f2e73c34cc0ef13f0b90dfbc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f30fc1540b6e0446e4a1be21f01c0299 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8db02b6583842c1066973dc388053707 |
| publicationDate | 2008-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-059917-A1 |
| titleOfInvention | PROTEASE INHIBITORS OF HEPATITIS C DEUTERATED. PROCESSES OF OBTAINING AND PHARMACEUTICAL COMPOSITIONS. |
| abstract | Processes for obtaining said compounds and pharmaceutical compositions containing them. Claim 1: An alpha-ketoamido compound enriched with deuterium of the formula (1), wherein: D denotes a deuterium atom; R1 as in formula (2) wherein the ring is an optionally substituted monocyclic azaheterocyclyl or optionally substituted multicyclic azaheterocyclyl or optionally substituted multicyclic azaheterocyclyl, wherein the unsaturation is in a distal ring relative to the ring bearing the R21 moiety and to which the R21 moiety is attached. residue -C (O) -N (R2) -CDR3-C (O) -C (O) -NR4R5; R21 is Q3-W3-Q2-W2-Q1; where each of W2 and W3 is, independently, a link, -CO-, -CS-, -C (O) N (Q4) -, -CO2-, -O-, -N (Q4) - C (O) -N (Q4) -, - N (Q4) -C (S) -N (Q4) -, -OC (O) NQ4-, -S-, -SO-, -SO2-, -N (Q4) -, -N (Q4) SO2-, -N (Q4) SO2N (Q4) - and hydrogen when any of W2 and W3 is the terminal group; each of Q1, Q2 and Q3 is, independently, a bond, an optionally substituted aliphatic, an optionally substituted heteroaliphatic, an optionally substituted cycloaliphatic, an optionally substituted aryl, an optionally substituted heteroaryl, an optionally substituted aralkyl or an optionally heteroaralkyl replaced; or hydrogen when any of Q3, Q2 or Q1 is the terminal group, with the proviso that Q2 is not a bond when both W3 and W2 are present; and each of R2, R3 and R4, independently, is H or a C1-6 alkyl; and R5 is H, alkyl, cycloalkyl, aryl optionally substituted with 1-4 alkyl, alkylaryl, aryl, amino groups optionally substituted with 1 or 2 alkyl groups. |
| priorityDate | 2006-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.