http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-057869-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 |
| filingDate | 2006-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-057869-A1 |
| titleOfInvention | QUATERNARY COMPOUND OF (ALPHA) -AMINOCARBOXYAMIDE, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE FOR THE MANUFACTURE OF A MEDICINAL PRODUCT AND PROCESS TO PREPARE SUCH COMPOUND |
| abstract | Pharmaceutical composition that comprises it and its use for the manufacture of a useful medicine to treat or prevent a disease or disorders mediated by modulation of the sodium channels with voltage opening ("voltage-gated"), such as depression or a state disorder emotional, bipolar or substance related disorder. Processes for preparing said compounds of formula (1). Claim 1: A quaternary alpha-aminocarboxamide compound characterized in that it is of formula (1), its pharmaceutically acceptable salt, solvate or prodrug: wherein R1 and R2 are independently H, C1-6 alkyl, or (C3-6 cycloalkyl) C1-6 alkyl; or these R1 and R2, together with the N to which they are attached, can form an unsubstituted saturated ring of 3, 4, 5 or 6 members; R3 is C1-6 alkyl, C1-6 haloalkyl, C1-3 alkenyl, (C1-3 alkoxy) C1-3 alkyl, (C1-3 haloalkyl) C1-3 alkyl or (CH2) tOH; or these R1 and R3, together with the interconnecting atoms, form a saturated or unsaturated ring of 5 to 7, with the proviso that there is only one heteroatom in the ring, which must be N; X is C or N; n is 0, 1 or 2, where, when present, each R4 is independently selected from the list consisting of C1-3 alkyl, halogen, cyano, C1-3 haloalkyl, hydroxy, C1-3 alkoxy and C1 haloalkoxy -3; q is 1 or 2; t is 1 or 2; either of R5 or R6 is -O-R7 or -OCH2R7, in which the other R5 or R6 is H or R4; and wherein R7 is a phenyl ring or a 5- or 6-membered aromatic heterocyclic ring (independently containing one or more N, S or O atoms), in which the phenyl ring or the heterocyclic ring is optionally substituted with one or more groups independently selected from the list consisting of C1-3 alkyl, halogen, cyano, C1-3 haloalkyl, hydroxy, C1-3 alkoxy and C1-3 haloalkoxy. |
| priorityDate | 2005-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.