| abstract |
A combined drug comprising a combination of a tetrazolilarkoxy-dihydrocarbostyryl derivative of the formula (1), wherein R is cycloalkyl, A is lower alkylene and the bond between positions 3 and 4 of the carbostyle nucleus is a single or double bond , or one of its salts and probucol, which is useful for preventing and treating cerebral infarction, which includes acute cerebral infarction and chronic cerebral infarction, arteriosclerosis, renal diseases (for example, diabetic nephropathy, renal failure, nephritis), and diabetes due for synergistic superoxide suppressing effects of the combination. |