http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-057450-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-417 |
| filingDate | 2006-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad0dd991d74d965662381a2fbec240e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bba9a5c7c17140a930eee047f2d2984 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73a326ebaa26768377d908b398975b6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90ab3a23054b339e0c10476d0a112b84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_383fecbc29ff6282c7f7cda1535219f5 |
| publicationDate | 2007-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-057450-A1 |
| titleOfInvention | DERIVATIVES OF N - [(1,2-DIFENIL-1H-IMIDAZOL-4- IL) METHYL] AMINA ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS |
| abstract | Procedure of preparation and therapeutic application. Claim 1: Compound of the formula (1) in which X represents a group -C (= O), -SO2-, -C (= O) -N (R6) -; R1 represents a C1-12 n alkyl substituted or substituted once or multiple times with substituents independently selected from an atom of F, hydroxyl, C1-4 alkoxy, phenoxy, a trifluoromethoxy moiety, difluoromethoxy, difluoromethylthio trifluoromethylthio; a non-aromatic (C3-12) carbocyclic moiety unsubstituted or substituted once or multiple times with substituents independently selected from C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, F atom, hydroxyl, trifluoromethyl, trifluoromethoxy, C1 alkyl -4-uncle; a C3-7-methylcycloalkyl unsubstituted or substituted once or multiple times in the carbocycle with substituents independently selected from C1-4 alkyl, C1-4 alkoxy, F, hydroxyl, trifluoromethyl, trifluoromethoxy, an unsubstituted or substituted one or multiple phenyl times with substituents independently selected from a halogen atom, hydroxyl, an Alc group, an OAlc group, methylenedioxy, C1-4-alkyl, C1-4 dialkyl, cyano, nitro, an S (O) nAlc, OS group (O) nAlc, C 1-4 alkylcarbonyl; or between a phenyl, phenoxy, pyrrolyl, imidazolyl, pyridyl or pyrazolyl moiety, wherein said substituent is unsubstituted or substituted once or multiple times with a C1-4 alkyl; a benzyl unsubstituted or substituted once or multiple times in the phenyl with substituents independently selected from a halogen atom, an Alc group, a hydroxyl, an OAlc group, a methylenedioxy, an S (O) nAlc, OS (O) nAlc group ; and unsubstituted or substituted in alpha with one or two same or different groups, selected from a C1-4 alkyl, a C3-7 cycloalkyl; a phenethyl unsubstituted or substituted once or multiple times in the phenyl with substituents independently selected from a halogen atom, C 1-4 alkyl, C 1-4 alkoxy, trifluoromethyl; trifluoromethoxy; a benzhydryl, a benzhydrylmethyl; a 1,2,3,4-tetrahydronaphthalene unsubstituted or substituted once or multiple times with a C1-4 alkyl; an aromatic heterocyclic moiety selected from a pyrrolyl, imidazolyl, furyl, thienyl, pyrazolyl, oxazolyl, pyridyl, indolyl, wherein said moiety is unsubstituted or substituted once or multiple times with substituents independently selected from a halogen atom or a C1- alkyl 4, C1-4 alkoxy, trifluoromethyl, trifluoromethoxy, cyano, nitro, C1-4 alkylthio; R2 represents an atom of H or C1-3 alkyl; R3 represents C1-5 alkyl; R4 represents a phenyl substituted once or multiple times with substituents independently selected from a halogen atom, an Alc group, an OAlc group, an S (O) nAlc or OS (O) nAlc group; R5 represents a phenyl substituted once or multiple times with substituents independently selected from a halogen atom, an Alc group, OAlc, an S (O) nAlc or OS (O) nAlc group; R6 represents an atom of H or C1-3 alkyl; n represents 0 1 or 2; Alc represents a C1-4 alkyl; not substituted or substituted once or multiple times with an atom of F; as well as its hydrate or solvate. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9458110-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11091447-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9126944-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9828345-B2 |
| priorityDate | 2005-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 31.