http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-056511-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fdb2b95ca7f4d374a06f2273bb1677b1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 |
| filingDate | 2006-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edabdcd8f6429bebe6bb422db7d43f62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc5accb130488dbbcc8a12537c21ef97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0ed551d7487e1c923b1ceae0afec541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c359b9e32ff0f9a23253fd436c4be10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01b9f6009ecacc928efe321377566bf7 |
| publicationDate | 2007-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-056511-A1 |
| titleOfInvention | DERIVATIVES OF 2-AMINOPIRIMIDINES, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE IN THE PREPARATION OF MEDICINES FOR THE TREATMENT OF DISEASES MEDIATED BY THE HISTAMINE RECEIVER H4 |
| abstract | These compounds are useful as modular of the activity of the H4 receptor, and are used as an active ingredient in the manufacture of drugs for the treatment of immunological or inflammatory diseases. Pharmaceutical compositions containing such derivatives are also provided. Claim 1: A compound of formula (1), characterized in that: R1 represents a group selected from formulas (2) to (4), R2 represents H or C1-4 alkyl; R3 represents phenyl optionally fused to a 5- or 6- membered aromatic, saturated or partially unsaturated, which may be carbocyclic or heterocyclic 1 or 2 heteroatoms selected from N, O and S, where R3 may be optionally substituted by one or more substituents R8; R4 represents H or C1-4 alkyl; R5 represents H or C1-4 alkyl; R6 represents H or C1-4 alkyl; R7 represents H or C1-4 alkyl; each R8 independently represents C1-4 alkyl, halogen, -OH, C1-4 alkoxy, C1-4 alkylthio, C1-4 haloalkyl, C1-4 haloalkoxy, -COR9, -CO2R9, -CONR9R9, -NR9R9, NHCOR10, -CN , C2-4 alkynyl, or -CH2OH, and additionally one of the R8 substituents may represent phenyl optionally substituted by one or more groups selected from C1-4 alkyl, halogen, -OH, C1-4 alkoxy, C1-4 alkylthio, C1-4 haloalkyl, C1-4 haloalkoxy, -COR9, -CO2R9, -CONR9R9, -NR9R9, -NHCOR10, -CN, C2-4 alkynyl, and -CH2OH; R9 represents H or C1-4 alkyl; R10 represents C1-4 alkyl; m represents 1, 2 or 3; n represents 0 or 1; and p represents 1 or 2; or a salt thereof. |
| priorityDate | 2005-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID774 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457574898 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458394811 |
Total number of triples: 34.