http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-055407-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-663 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-663 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-10 |
| filingDate | 2006-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-055407-A2 |
| titleOfInvention | GEL TYPE AQUATIC PHARMACEUTICAL COMPOSITION FOR SUBCUTANEOUS ADMINISTRATION, PROCEDURE FOR THE PREPARATION AND USE OF SUCH COMPOSITION FOR THE PREPARATION OF A MEDICINAL PRODUCT |
| abstract | A gel-like aqueous pharmaceutical composition for subcutaneous administration, comprising bisphosphonic acids or their pharmaceutically acceptable salts. The composition has at least one compound that inhibits the diffusion of the active substance in the tissue, the active substance being present in dissolved form in the composition, and the composition having a viscosity> -220 mPa * s. A process for the production of this composition and the use of said compositions for the preparation of a medicament are also disclosed. Through this composition it is possible to locally administer relatively high concentrations of bisphosphonates without incompatibilities, to treat bone metabolism disorders. Claim 1: Gel-like aqueous pharmaceutical composition for subcutaneous administration, comprising bisphosphonic acids selected from: clodronate, etidronate, risedronate, zoledronate, tiludronate, pamidronate, cimadronate (YM175) and alendronate, or its physiologically acceptable salts, characterized in that it contains at least one compound that inhibits the diffusion of the active substance in the tissues, which is a natural polymer and is selected from the group consisting of cellulose derivatives, alginic acid derivatives, dextrans, gelatins, collagen, hyaluronic acids and / or dermatan and heparan sulfates, the active substance being present in dissolved form in the composition and the composition having a viscosity> - 220 mPa * s. |
| priorityDate | 2000-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.