http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-055398-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b4a80ac02f1ecd0e698ec665e9b36b6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1641 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2031 |
| filingDate | 2006-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20a9806ccb003dfa3d641aa69ad7651e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3205e7c10b907726ff7f6c5d4659f86c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3632d42c3c7466e851ab251fb01df5de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2da1c48b936ff86678042e607b808f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9a4aedd84438f1dd317542b60cd08f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c8142489ed8afd31b624cf5a1f6f3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac288015970761595558f59b2abe0e47 |
| publicationDate | 2007-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-055398-A1 |
| titleOfInvention | PHARMACEUTICAL COMPOSITION OF SOLID DISPERSION OF PRANLUKAST WITH BETTER RATE OF INITIAL DISSOLUTION AND METHOD TO PREPARE THE COMPOSITION |
| abstract | Pharmaceutical composition of a solid dispersion of pranlukast with a better initial dissolution rate and method for its preparation. More specifically, a pharmaceutical composition of a solid dispersion of pranlukast prepared by mixing a solid dispersion of pranlukast with an anticoagulant agent with a determined range of HLB at an elevated temperature, which can be processed as granules and encapsulated, enabling an improvement of the pharmaceutical composition is described. initial dissolution rate of pranlukast. The serious problem of the adhesion of solid dispersions of pranlukast to the capsule walls is solved and the bioavailability is improved by presenting higher Cmax and AUC values compared, based on the same administration dose, with the commercial pharmaceutical compositions of pranlukast formulated with conventional methods; and method of preparation. Claim 1: A pharmaceutical composition of solid dispersion of pranlukast characterized in that it comprises 100 parts by weight of solid dispersion of pranlukast and between 0.1 and 10 parts by weight of anticoagulation agent, which is in solid or semi-solid state at temperature environment and has 10-40 of HLB. |
| priorityDate | 2005-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419491693 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID115100 |
Total number of triples: 26.