http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-053409-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| filingDate | 2005-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2007-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-053409-A1 |
| titleOfInvention | 4- (2,4-DICLORO-5-METOXIFENIL) AMINO-6-METOXI-7 - ((5- (AMINO-REPLACED) METHYL) -3-FURIL) -3-CHINOLINCARBONITRILS AS QUINASE INHIBITORS. PROCESSES OF OBTAINING AND PHARMACEUTICAL COMPOSITIONS. |
| abstract | Obtaining processes and pharmaceutical compositions containing them. Claim 1: a compound of formula (1) wherein: R1 and R2 may be the same or different, and are selected from H, C1-6 alkyl, (CH2) nXR4, (CH2) nNZZ ', C2-6 alkenyl, C2 alkynyl -6, aryl or heteroaryl; R1 and R2 can be taken together with the N to which they are attached to form a heterocyclic ring which, optionally, has an additional heteroatom selected from N, O and S, where the S may be mono- or di-oxidized, optionally substituted with at least one -R3 in a C or N, or in N with a group - (CH2) nXR4, - (CH2) nNZZ ', or in C with a group - (CH2) qXR4, - (CH2) qNZZ ', halogen; Z and Z 'are selected from H, C 1-6 alkyl, C 2-6 alkenyl, C 2-6 alkynyl, aryl or heteroaryl; and Z and Z 'can be taken together with the N to which they are attached to form a heterocyclic ring which, optionally, contains an additional heteroatom selected from N, O and S; R3 is C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, O, alkylaryl, alkylheteroaryl, cycloalkyl, aryl or heteroaryl; wherein the aryl or heteroaryl is optionally substituted with one or more C1-6 alkyl, C1-6 alkoxy, halogen, -OH, alkylhydroxy or trifluoromethyl; R4 is H, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, aryl or heteroaryl; X is O, S, NR4; n is 2-5; q is 0-5; and its pharmaceutically acceptable salts. |
| priorityDate | 2004-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID457311044 |
Total number of triples: 12.