http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-051010-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2aac90f6ae135d9b90a2fcf43227c605 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84bf3df3c637864eb72d38d2bb2eee7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7249f1e85ea88a8e48937bf84599b792 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-06 |
| filingDate | 2005-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bac9c9d58cf7e751ddf9fdc8f07f4e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0149131a30f98aa906cba471bddf222f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d954fc7391264e363e2853990153b7cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b921966aed897bfa70cdf2365836352 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c926973ed18fb21ec0a5a78a180e19dd |
| publicationDate | 2006-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-051010-A1 |
| titleOfInvention | R-SALBUTAMOL SULPHATE CRYSTALLINE POLYMORPHES, PROCEDURES FOR OBTAINING THEM, PHARMACEUTICAL FORMULATIONS THAT INCLUDE THEM AND THEIR USE IN THE PREPARATION OF MEDICINES WITH ACTION ON b₂-ADRENERGIC RECEPTORS |
| abstract | Polymorphic crystalline forms of R - (-) - salbutamol sulfate ((R) - (-) - [1- (4-hydroxy-3-hydroxymethylphenyl) -2-t-butylamino] ethanol sulfate), processes for its preparation and pharmaceutical compositions that comprise them, and their use in the preparation of a medicament for the treatment of asthma, premature births, and also usable as anabolic. Claim 1: Crystal polymorphs of R-Salbutamol Sulfate of Forms I and II, characterized in that said Forms I and II exhibit a DRX-P pattern with characteristic exclusive peaks expressed in degrees 2q ± 0.2 °, at approximately 10, 7; 11.9 and 12.6 and 8.7; 9.6 and 15.2, respectively. Claim 21: A process for the preparation of the Formula I of R-salbutamol Sulfate according to claim 1 characterized in that it comprises: (i) heating a supersaturated methanolic solution of R-salbutamol Sulfate to 40 ° C; and (ii) cool the solution. Claim 24: A process for the preparation of R-salbutamol Sulfate Formula II according to claim 1 characterized in that it comprises: (i) heating a supersaturated methanolic R-salbutamol sulfate solution to 60 ° C; and (ii) cool the solution. |
| priorityDate | 2005-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.