http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-050698-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-10 |
| filingDate | 2005-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-050698-A1 |
| titleOfInvention | BENZAZEPINE COMPOUND, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE FOR THE MANUFACTURE OF A MEDICINAL PRODUCT AND PROCEDURE FOR THE PREPARATION OF SUCH COMPOUND |
| abstract | Compound of benzazepine, or its pharmaceutically acceptable salt, of formula (1), wherein R 1 represents C 1-6 alkyl or C 3-7 cycloalkyl, the C 3-7 cycloalkyl group may be optionally substituted with C 1-3 alkyl; R7 represents hydrogen, C1-6 alkyl or aryl; R2 represents -aryl, -heteroaryl, -C3-8-Y-cycloalkylC3-8, -C3-8-Y-arylcycloalkyl, -C3-8-Y-heteroaryl-cycloalkyl, -C3-8-Y-heterocyclyl, -aryl-Y -C3-8cycloalkyl, -aryl-Y-aryl, -aryl-Y-heteroaryl, - aryl-Y-heterocyclyl, -heteroaryl-Y-C3-8 cycloalkyl, -heteroaryl-Y-aryl, -heteroaryl-Y-heteroaryl, - heteroaryl-Y-heterocyclyl, -heterocyclyl-Y-cycloalkylC3-8, -heterocyclyl-Y-aryl, -heterocyclyl-Y-heteroaryl or -heterocyclyl-Y-heterocyclyl, so that R2 is linked to A through an atom of carbon; Y represents a bond, C1-6 alkyl, CO, CONH, C2-6 Coalkenyl, O, SO2 or NHCOC1-6 alkyl; R3 represents halogen, C1-6 alkyl, C1-6 alkoxy, cyano, amino or trifluoromethyl; n is 0, 1 or 2; said alkyl, cycloalkyl, aryl, heteroaryl and heterocyclyl of R2 may be optionally substituted with one or more substituents (eg, 1, 2 or 3) which may be the same or different selected from halogen, hydroxy, cyano, nitro, = O , SO2H, -R4, -CO2R4, -COR4, -NR5R6, -alkylC1-6-NR5R6, -cycloalkylC3-8-NR5R6, -CONR5R6, -NR5COR6, -NR5SO2R6, -OCONR5R6, -NR5N2R6R6R6R6R6R6R6R6R6R6R6R6R6R6R6R6 SHR8, -alkyl-OR8, -SOR8, -OR9, -SO2R9, -OSO2R9, -alkyl-SO2R9, -alkyl- CONHR9, -alkyl-SONHR9, -alkyl-COR10, -CO-alkyl-R10, -O-alkyl -R11 (where R4, R5 and R6 independently represent hydrogen, C1-6 alkyl, -C3-8 cycloalkyl, -C1-6 alkyl-C3-8 alkyl, aryl, heterocyclyl or heteroaryl, wherein R8 represents C1-6 alkyl, in where R9 represents C1-6 alkyl or aryl, where R10 represents aryl, where R11 represents C3-8 cycloalkyl or aryl, and where -NR5R6 can represent a heterocyclic group containing nitrogen); said groups R4, R5, R6, R8, R9, R10 and R11 may optionally be substituted with one or more substituents (eg, 1, 2 or 3) selected or selected from halogen, hydroxy, C1-6 alkyl, C1 alkoxy -6, cyano, amino, = O or trifluoromethyl; or his solvates. Pharmaceutical composition comprising them and use of said compounds for the manufacture of a medicament, useful for the treatment of neurological diseases. Procedure for the preparation of said compounds. These compounds are applied in neurology and psychiatry. |
| priorityDate | 2004-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.