http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-049500-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D275-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-03 |
| filingDate | 2005-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2006-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-049500-A1 |
| titleOfInvention | PHENYLATE DERIVATIVES FOR THE TREATMENT OF ABNORMAL CELLULAR GROWTH |
| abstract | Phenyl derivatives useful for treating a hyperproliferative disorder in a mammal. Pharmaceutical compositions that contain them. Claim 1: A substantially pure compound characterized in that it responds to formula (1), wherein: X1, X2 and X3 are independently a halogen; p is an integer between 1 and 3; and R is OR1, where R1 is a substituted isothiazole ring, or SR2 where R2 is (CH2) qC (COOH) (NHC (O) R3), where q is an integer between 0 and 3, and R3 is C1 alkyl -4; or a salt, solvate or prodrug thereof acceptable for pharmaceutical use. Claim 2: The compound according to claim 1, characterized in that said compound responds to formula (2), wherein: t is an integer between 3 and 5; and R4 is -COOH, -NH (CH2) kOH, where k is an integer between 1 and 5, -NH (CH2) lCOOH, where l is an integer between 1 and 5, or a 5-membered heterocycle containing nitrogen, which may optionally be substituted with one or more portions oxo (= O), hydroxyl groups, or where there is an oxygen atom attached to the nitrogen atom of the 5-membered heterocycle containing nitrogen to form an N-oxide group (NO ). |
| priorityDate | 2004-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.