http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-045476-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f3ebf63d28f804e0a154cf8da0ccf2c6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-3813 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-28 |
| filingDate | 2004-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_097b1aca752b550551f8e2e3d349e3c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5bd9057217234bfddcaf3aecbea568d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42147254743ce4a7d44be35287bfc50e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b9cac6d7b1b5ba6ce1a98a3eedc7054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4345c27f56df08638a89fb27d86965ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f778eb90ccadbb5f270573581a942740 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eda836ef908251dfe62b3cc08569a310 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f27406e782f2170083ffac7200edf4c |
| publicationDate | 2005-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-045476-A1 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF N-PHOSPHONE-METHYLGLYCIN AND DERIVATIVES OF THE SAME |
| abstract | Production of N-phosphonomethylamines by means of the reaction of an amine substrate with halomethylphosphonic acid or a salt thereof, a hydroxymethylphosphonic acid or a salt thereof, or a dimer, trimer or oligomer of a dehydrated auto-ester of the hydroxymethylphosphonic acid, between The products that can be prepared according to the process are N-phosphonomethylaminocarboxylic acids such as (for example) glycosate, N-phosphonomethylaminoalkanes such as (for example) hydroxymethylaminophosphonic acid, and N-acylaminomethylphosphonic acids such as (for example) N-carbamylaminomethylphosphonic acid. Certain reactions are carried out with a significant excess of amine reagent to direct the conversion while avoiding excessive formation of bis (N-phosphonomethyl) amine by-products. Other reactions employ a secondary amine substrate (such as iminodiacetic acid) and can be carried out in practically equimolar ratios of halomethylaminophosphonic acid or hydroxylaminomethylphosphonic acid to secondary reactant amine without significant formation of bis (phosphonomethyl) amine by-products. In addition, a process for the preparation of self-esters of dimers, trimers and oligomers of hydroxymethylphosphonic acid by azeotropic dehydration is described. Claim 1: A process for the preparation of a product characterized in that it corresponds to the formula (1): (HO) 2-P (P) -CH2-NR1-C (R2 (R3) -R4 (1), or an ester of the phosphonic acid or a salt thereof, wherein R1 is selected from the group consisting of hydrogen and an alkyl, alkenyl, alkynyl, aryl, aralkyl, aralkenyl or substituted or unsubstituted aralkunyl group, R2 and R3 are independently selected from the group consisting of hydrogen , nitro, cyano and an substituted or unsubstituted alkyl, alkenyl, alkynyl, aryl, aralkyl, aralkenyl or aralkynyl group and R4 is selected from the group consisting of cyano and a substituent corresponding to formula (2), where R5 is hydrogen or a radical that forms a carboxylate salt or an ester, and the process comprises: contacting a halomethylphosphonic acid or a salt thereof with a reactive amine comprising a compound corresponding to the formula (3): R1-NH-C ( R2) (R3) -R4 (3), where R1, R2, R3 and R4 have the va Lords that have been defined, or a dimer, oligomer or polymer of a compound of formula (3) in which R4 corresponds to formula (2), in a reaction of at least about 1.5 moles of said reactive amine per mole of halomethylphosphonic acid. |
| priorityDate | 2003-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.