http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-045113-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4dac022280ec96f54c694eb427655932 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 |
| filingDate | 2004-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-045113-A1 |
| titleOfInvention | SUBSTITUTED DERIVATIVES OF TIAZOLBENZOISOTIAZOL DIOXIDE, PROCEDURE FOR PREPARATION AND USE |
| abstract | This refers to compounds of substituted thiazol-benzoisothiazole dioxide derivatives, and their physiologically acceptable salts, which are suitable as medicaments for producing blood glucose and for the prevention and treatment of diabetes. It also refers to the procedure for its preparation. Claim 1: A compound of the formula (1) in which the meanings are R1, R2 independently of one another, H, aryl, COOH, (C1-6) alkylene -COOH, -COO-(C1-6) alkyl, alkylene (C1-6) -COO-(C1-6) alkyl, (C1-6) alkyl, (C2-6) alkenyl, (C1-6) -aryl, heterocycle, (C1-6) -heterocycle alkylene, CF3 , OCF3, CN, (CH2) 1-6-OH, O-C 1-6 alkyl, CO-C 1-6 alkyl, -C (O) O-alkyl, COOH, CON (R9) (R10) ), wherein the aryl radicals and heterocycle radicals may be substituted one or more times with F, Cl, Br, (CH2) 0-2-OH, (C1-6) alkyl, (C2-6) alkenyl, alkynyl ( C2-6), CF3, OCF3, N (R9) (R10), piperidinone, piperazine, piperazinone, N- (alkylene- (C1-6) -piperazine, N- (alkylene (C1-6)) - piperazinone, morpholine , thiomorpholine, NO2, CN, O-C1-6 alkyl, S (O) 0-2-C1-6 alkyl, SO2-N (R9 (R10), CO-C1-6 alkyl), - COOH, (C1-6) alkylene -COOH, COO-C1-6 alkyl, alkylene (C1-6) -COO-alkyl (C1-6), cycloalkyl (C3-10), phenyl, where are you piperidinone, piperazine, piperazinone, N -alkylene (C1-6-piperazine, N- (alkylene (C1-6) -piperazinone, morpholine, thiomorpholine and phenyl rings may be substituted one or more times with F, Cl, Br, (CH2) 0-2-OH, COOH, CN, NO2, -O-C1-6 alkyl, -NH-O-C1-6 alkyl, - (CO) -NH-O-C1-6 alkylene -N- (R9) ( R10), - (CO) -alkyl (C1-6), -alkyl (C1-6), CF3, OCF3, N (R9) (R10); R3 H, (C1-6) alkyl, (C1-6) -aryl, -C (O) -aryl, (C1-6) -heterocycle, CO-(C1-6) alkyl, wherein aryl radicals and heterocycle may be substituted one or more times with F, Cl, Br, (C1-6) alkyl, COOH, COO-(C1-6) alkyl, CF3 or OCF3; R4, R5 independently of each other: H, F, Cl, Br, (C1-6) alkyl, CF3, OCF3, NO2, N (R9) (R10), CN, O-alkyl- (C1-6), CO- (C1-6) alkyl, COOH, (C1-6) -COOH, CON (R9) (R10), (C1-6) -CON (R9) (R10), COO-(C1-6) alkyl, alkylene (C1-6) -COO-alkyl (C1-6), S (O) 0-2-alkyl (C1-6), S (O) 2-N (R9) (R10), CH2OH, CH2OCH3; R6, R7 independently of each other, H, F, CL, Br, (C1-6) alkyl, cyclopropyl, tetrafluoro-cyclopropyl, difluoro-cyclopropyl, or R6 and R7 together form the group = CH2; R8 H, CH3, CF3, CH2OH; R9 H, (C1-4) alkyl; R10 H, (C1-4) alkyl; or R9 and R10 form, together with the N atom to which they are attached, a 3-9 member ring system; and its physiologically acceptable salts. |
| priorityDate | 2003-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 36.