http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-044874-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 |
| filingDate | 2004-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40d9436ce2b7a2afed9d33eed4c5f210 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26a09701d59d5e6719c30ebdfdcf49a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73a326ebaa26768377d908b398975b6e |
| publicationDate | 2005-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-044874-A1 |
| titleOfInvention | DERIVATIVES OF 4- CIANOPIRAZOL-3 - CARBOXAMIDE, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS |
| abstract | It refers to 4-cyanopyrazol-3-carboxamide derivatives and pharmaceutical composition containing it. Claim 1: Compound that responds to formula (1), in which: R 1 represents hydrogen or a (C 1-4) alkyl; R2 represents: a (C3-7) alkyl group; a C3-10 non-aromatic carboxylic radical, unsubstituted or substituted once or several times by a (C1-4) alkyl and / or hydroxyl group; a phenyl substituted by a halogen atom and / or by a (C1-4) alkyl and / or trifluoromethyl and / or (C1-4) alkoxy group; an NR9R10 group; a CH [C1-4)] -benzhydryl group in which one or both phenyl groups are unsubstituted or substituted once or several times by a halogen atom and / or by a (C1-4) alkyl group and / or (C1-4) alkoxy; or R1 and R2 together with the nitrogen atom to which they are attached constitute a piperidin-1-yl radical substituted in 4- by a phenyl or benzyl group and by a (C1-4) alkyl group or a (C1-3) alkanoyl group ; R3, R4, R5, R6, R7, R8 each independently represent a hydrogen or halogen atom, a (C1-6) alkyl, (C1-6) alkoxy or trifluoromethyl group; provided that at least one of the substituents R3, R4, R5, R6, R7, R8 is different from hydrogen; R9 represents a hydrogen atom; R10 represents a (C3-6) alkyl; or R9 and R10 together with the nitrogen atom to which they are attached constitute a heterocyclic radical, saturated or unsaturated, of 5 to 10 atoms, containing, or not, a second heteroatom chosen from O or N, and said radical is a radical not substituted or substituted once or several times by a (C1-4) alkyl and / or hydroxyl and / or alkoxy (C1-4) and / or methoxyalkylene (C1-2) and / or alkanoyl (C1-4) group, or substituted by a spirocyclobutane, a spirocyclopentane or a spirocyclohexane; in a state of base or salt of addition with an acid, as well as in a state of hydrate or solvate. |
| priorityDate | 2003-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.