http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-044019-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-401 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-16 |
| filingDate | 2004-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2005-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-044019-A1 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF N-SUBSTITUTED 2-CYANOPIRROLIDINS |
| abstract | This refers to a process for the preparation of a 2-cyanopyrrolidine N- (substituted N'-glycyl), comprising at least: a) reacting, in the presence of dimethylformamide, a compound of the formula (1), wherein, independently of each other, X1 and X3 are halogen; X2 is halogen, OH, OC (= O) -CH2X3, -O-SO2-alkyl (C1-8) or -O-SO2 (aryl), with L-prolinamide, followed by: b) reacting the resulting compound without isolation with a dehydration agent, optionally followed by: c) reacting, in the presence of a base, the resulting compound without isolation with an appropriate amine, and d) recovering the resulting compound in free form or as an acid addition salt . |
| priorityDate | 2003-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.