http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-043963-A1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_31f0671f1cf0d5d99264bdf01e2579f5 |
filingDate | 2004-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2005-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-043963-A1 |
titleOfInvention | DERIVATIVES OF BENCIMIDAZOL AND ITS USE TO MODULATE THE GABA RECEIVER COMPLEX TO |
abstract | This refers to benzimidazole derivatives, pharmaceutical compositions containing these compounds and methods of treatment therewith. The compounds herein are useful in the treatment of diseases and disorders of the central nervous system, which respond to the modulation of the GABAA receptor complex, and in particular, to combat anxiety and related diseases. Claim 1: A compound of the general formula (1), or an N-oxide thereof, or any of its isomers or any mixture of its isomers, or a pharmaceutically acceptable salt thereof, in which: R represents hydroxyalkyl, alkoxyalkyl, cycloalkoxyalkyl, cycloalkylalkoxyalkyl, alkenyloxyalkyl or alkynyloxyalkyl; and R 'represents a five-membered heterocyclic ring; which may be optionally substituted with one or more independent substituents selected from the group consisting of halo, hydroxy, amino, alkylamino, aminoalkyl, cyano, nitro, trifluoromethyl, trifluoromethoxy, alkoxy, cycloalkoxy, alkyl, cycloalkyl, cycloalkylalkyl, alkenyl and alkynyl. |
priorityDate | 2003-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 13.