http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-041955-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae84948901b77f34fd51c41264d8d19c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-06 |
| filingDate | 2003-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a475ca8625a5e844476af319aaa89d1d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f38fad242f4bbde89290cb3aa90b66dd |
| publicationDate | 2005-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-041955-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF IMIDAZOLIL COMPOUNDS |
| abstract | This refers to a method for the preparation of an imidazolyl compounds of the general formula (1), wherein: Ra and Rb each separately are (C1-6) alkyl, (C1-6) alkoxyalkyl, aryl or heteroaryl optionally substituted; or wherein Ra and Rb together form an additional homocyclic or heterocyclic system comprising one or more rings; Ra 'and Rb' are each hydrogen or together form a carbon-carbon double bond, said carbon-carbon double bond being optionally part of an aromatic system; Rc is hydrogen, (C1-6) alkyl, (C-16) alkoxy, (C1-6) alkoxyalkyl or halogen; Rd is hydrogen or (C1-4) alkyl; Re is hydrogen or (C1-4) alkyl; m is 1 or 2; and R1 is hydrogen or (C1-4) alkyl; as well as its acid addition salts; characterized in that a compound of the general formula (2) is reacted with a compound of the formula (3), wherein: R is hydrogen, an alkyl (C1-4) group optionally substituted with an alkoxy group or an aryl group optionally substituted, R ', R' ', R' '', R '' '' each individually is a hydrogen or a (C 1-4) alkyl group, followed by reaction with a compound of the formula (4), where R1, Rd and Re have the meanings defined above; and optionally followed by reaction with a suitable acid. The method according to the present is especially useful for the preparation of ondansetron and cilansetron |
| priorityDate | 2002-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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