http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-040441-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27a71ddaaa2f5a8c228fc6cb3f3b3098 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 |
filingDate | 2003-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2005-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | AR-040441-A1 |
titleOfInvention | TIOL COMPOSITE, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, ITS USE FOR THE MANUFACTURE OF A MEDICINAL PRODUCT, PROCEDURE TO PREPARE IT AND INTERMEDIATE COMPOSITE OF UTILITY IN THIS PROCEDURE |
abstract | A thiol compound having the formula (1) in which R 1 represents C 1-6 alkyl; R2 represents pyrazole or pyrimidine, or one of its pharmaceutically acceptable derivatives. Pharmaceutical composition comprising a compound of the formula (1) together with a pharmaceutical vehicle and / or excipient and use of said compound for the manufacture of a medicament for the treatment of a patient suffering from a disease susceptible of being relieved by an inhibitor of ECA and / or EPN. Process for preparing a compound of formula (1) and intermediate compound useful in said process. Claim 9: A process for preparing a compound of formula (1) according to any one of claims 1 to 5, characterized in that it comprises reacting a compound of formula (2) with a compound of formula (3), followed by deprotection wherein R1 represents C1-6 alkyl; R2 represents pyrazole or pyrimidine; and P1 represents an oxygen protecting group. |
priorityDate | 2002-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.