| abstract |
A process for preparing an alkaloid reaction product that can be converted into a water soluble form, comprising the steps of: a) preparing a reaction product by reacting at least one alkaloid with a phosphorus derivative containing at least one aziridine -N group (CH2CH2) according to the general formula (1), in an organic solution at elevated temperature, in particular at the boiling temperature of the solvent, and b) washing the reaction product obtained in step a); characterized in that said reaction product is washed with water. The reaction products obtained are suitable as drugs. This process promotes the conversion of alkaloids into a water-soluble form. In particular, it allows to convert, in addition to the selected alkaloids, the total alkaloids of Chelidonium majus L and then obtain a low toxicity pharmaceutical preparation with such a wide spectrum of action. as possible. Also described are the reaction products obtained with said process, a mixture of these reaction products, and the use of said reaction products as drugs intended for the prophylaxis or treatment of diseases or organic dysfunctions selected from the group formed for cancer, immune diseases and metabolic diseases, in particular, osteoporosis, allergies, skin tumors, viral infections, rheumatic diseases, scars, postoperative lesions, epilepsy and multiple sclerosis. |