| abstract |
Multi-layer, controlled-release tablet, comprising: (a) an active layer containing: (i) ropinirole or a pharmaceutically acceptable salt thereof, as active substance, (ii) hydrophilic polymeric substances that swell and / or gel and / or erode on contact with aqueous liquids; (iii) lipophilic substances and (iv) adjuvant substances, in which the weight ratio of hydrophilic polymeric substances to lipophilic substances contained in said active layer is in the range of 10: 1 to 0.5: 1; and (b) one or more barrier layers containing one or more hydrophilic polymeric substances that swell and / or gel and / or erode on contact with aqueous liquids, lipophilic substances and adjuvant substances; said tablet being useful in a method for the treatment of fibromyalgia. Use of said multilayer tablet, controlled release, for the manufacture of a medicament useful in the treatment of fibromyalgia. A pharmaceutical composition comprising the multilayer tablet, controlled release, described for use in the treatment of fibromyalgia. |