http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-036354-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2813 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-28 |
| filingDate | 2002-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1637c83eee18536456c070f3e8d9a3d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_007ef00acccaacbe18182184dcfd2fdd |
| publicationDate | 2004-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-036354-A1 |
| titleOfInvention | SOLID PREPARATION |
| abstract | A solid gastric disintegrable preparation comprising an active acid-inactivating active ingredient and rapid stomach neutralizing acid that suppresses the generation of carbonic anhydride allowing the pharmacological effect of the active ingredient, and at least one component selected from the metal oxides e metal hydroxides, whose decay time is preferably within 7 minutes. In addition, said preparation has no enteric layer. The preparation additionally comprises at least one component selected from the alkali and earth metal carbonates and the basic additives having a high water solubility. The acid-inactivating active ingredient is a compound represented by the formula (1) wherein ring A is an optionally substituted benzene ring, R1 is hydrogen atom, an optionally substituted aralkyl group, acyl group or acyloxy group, R2, R3 and R4 are the same or different and each represents a hydrogen atom, an optionally substituted alkyl group, an optionally substituted alkoxy group or an optionally substituted amino group, and Y represents a nitrogen or CH atom, or a salt thereof. The metal oxide is selected from the group consisting of magnesium oxide, magnesium silicate, dry aluminum hydroxide gel and magnesium metasilicate aluminate and the metal hydroxide is selected from the group consisting of magnesium hydrate, aluminum hydroxide , synthetic hydrotalcite, coprecipitate of aluminum hydroxide and magnesium hydroxide, coprecipitate of aluminum hydroxide, magnesium carbonate and calcium carbonate, and coprecipitate of aluminum hydroxide and sodium bicarbonate. |
| priorityDate | 2001-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.