http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-035420-A1

Outgoing Links

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4188
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filingDate 2002-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2004-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber AR-035420-A1
titleOfInvention A PROCESS FOR THE PREPARATION OF A COMPOUND IMIDAZO-TETRAZIN-4-ONA AND A PROCESS FOR THE PREPARATION OF TEMOZOLOMIDE AND INTERMEDIARIES
abstract A process for the preparation of an imidazo-tetrazin-4-one compound of the formula (1) in which R is a C1-6 alkyl group, which comprises the reaction of a compound of the formula (2) in which R it is as defined above, with an oxidation / cyclization agent in the presence of an iodide, in an inert medium, under an inert atmosphere and at a temperature and for a period sufficient to produce a compound of the formula (1), where said iodide It is soluble in said inert medium, and a process for the preparation of temozolomide and intermediates. Anti-tumor
priorityDate 2001-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 21.