| abstract |
An azol compound of neurotrophin production / secretion that responds to formula (1), wherein: R 1 represents a halogen atom, a heterocyclic that can be optionally substituted, hydroxyl that can be optionally substituted, a thiol that can be optionally substituted, or an amino that can be optionally substituted; A represents an acyl that can be optionally substituted, a heterocyclic that can be optionally substituted, a hydroxyl that can be optionally substituted, or a carboxyl that can be optionally esterified or amidated; B represents an aromatic group that can be optionally substituted; X represents an oxygen atom, sulfur atom, or nitrogen atom that can be optionally substituted; and Y represents a bivalent or heterocyclic hydrocarbon, or a salt thereof, useful for preventing or treating neuropathy. A compound prodrugs neurotrophin production / secretion promoter comprising a prodrug of an azol compound, or a salt thereof, as described. A pharmaceutical composition comprising said azol compound and use thereof to prepare it. |