| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8ec35c2549b36b67e202b24d68d7193 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2002-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2004-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
AR-034356-A1 |
| titleOfInvention |
INSULINIC-OLIGOMERO DRUG CONJUGATES MIXING POLYCHYLENGLYCOL, USES OF THE SAME, AND METHODS OF OBTAINING |
| abstract |
A mixture of conjugates is described in which each conjugate of the mixture comprises an insulin drug coupled to an oligomer that includes a polyalkylene glycol moiety. The mixture may exhibit greater activity in vivo than a polydispersed mixture of similar conjugates. The mixture may also be more effective in survival in an in vitro model of intestinal digestion than polydisperse mixtures of similar conjugates. The mixture may also have less inter-subject variation than polydisperse mixtures of similar conjugates. |
| priorityDate |
2001-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |