http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-032896-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4fda45c540f11df3a7fe71d54a70562a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2001-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-032896-A1 |
| titleOfInvention | ARILALCANO-SULFONAMIDS, PHARMACEUTICAL COMPOSITIONS, A PROCESS FOR THEIR PREPARATION, AND THE USE OF THE SAME FOR THE PRODUCTION OF PHARMACEUTICAL COMPOSITIONS |
| abstract | Arylalkano-sulfonamides, which comprise compounds of the general formula (1) in which R1 and R2 represent aryl, heteroaryl, R3 represents phenyl; mono-, di or tri-substituted phenyl with lower alkyl, lower alkenyl, lower alkynyl, phenyl, lower alkoxy, amino, lower alkylamino, lower alkyl-amino, trifluoromethyl, trifluoromethoxy, halogen, lower alkylthio, hydroxy, hydroxy-lower alkyl, cyano, carboxyl, lower alkanoyl, formyl; benzofuranyl; aryl; heteroaryl; R4 represents hydrogen, halogen, trifluoromethyl; lower alkyl; lower alkyl amino; lower alkoxy; lower alkyl sulfone; lower alkyl sulfinyl; lower alkylthio; lower alkylthio-lower alkyl; hydroxy-lower alkyl, alkyl-oxy-lower alkyl; hydroxy lower alkyl oxy lower alkyl, hydroxy lower alkyl amino; lower alkyl amino lower alkyl; Not me; di-lower alkyl amino; [N- (hydroxy-lower alkyl) -N- (lower alkyl)] -amino; aryl; aryl amino; aryl-lower alkyl-amino; alkyl amino; aryl-uncle; aryl-lower alkyl-thio; aryloxy; aryl lower alkyl oxy; aryl-lower alkyl; aryl sulfinyl; heteroaryl; heteroaryl-oxy; heteroaryl-lower alkyl-oxy; heteroaryl amino; heteroaryl-lower alkyl amino; heteroaryl-thio; heteroaryl-lower alkylthio; heteroaryl-lower alkyl; heteroaryl sulfinyl; heterocyclyl; heterocyclyl-lower alkyl-oxy; heterocyclyl-oxy; heterocyclyl amino; heterocyclyl-lower alkylamino; heterocyclylthio; heterocyclyl-lower alkylthio; heterocyclyl-lower alkyl; heterocyclyl sulfinyl; cycloalkyl; cycloalkyl-oxy; cycloalkyl-lower alkyl-oxy; cycloalkyl amino; cycloalkyl-lower alkyl amino; cycloalkylthio; cycloalkyl-lower alkylthio; cycloalkyl-lower alkyl; cycloalkyl sulfinyl; X represents oxygen; sulfur; NH; CH2 or a link; Y represents oxygen, sulfur or ûNH-; Z represents oxygen; sulfur, -NH- or a bond; Q represents û (CH2) k-; - (CH2) m-CsC- (CH2) p-, in case p represents 0 (zero), Z represents a bond; -CH2-cyclopropylene-CH2-; k represents the numbers 2, 3, 4, 5 or 6; m represents the numbers 1, 2 or 3; p represents the numbers 0, 1, 2 or 3; n represents the numbers 1, 2 or 3; and pure diastereomers, mixtures of diastereomers, diastereomeric racemates, mixtures of diastereomeric racemates and meso-forms and their pharmaceutically acceptable salts; pharmaceutical compositions, a process for their preparation, and the use thereof for the production of pharmaceutical compositions. The compounds are endothelin antagonists. |
| priorityDate | 2000-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.