| abstract |
The invention relates to a method of treatment of indications that can be positively influenced by inhibition of effects that mediates AT1 with maintenance of effects of Angiotensin II that mediates the AT2 receptor and by ACE inhibition, thus also increasing the effects. that mediates bradykinin, for example decrease in the incidence of apopletic shock, acute myocardial infarction or cardiovascular death, or indications associated with the increase of AT1 receptors in the subepithelial zone or the increase of AT2 receptors in the epithelium, which It comprises the co-administration of effective amounts of an Angiotensin II antagonist and an ACE inhibitor, to pharmaceutical compositions containing an Angiotensin II antagonist together with an ACE inhibitor, and to the use of an Angiotensin II antagonist. and an ACE inhibitor for the manufacture of the corresponding pharmaceutical compositions. |