http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AR-030056-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bde28565d28f037e78bf4a67776ee24 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01L21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 |
| filingDate | 2001-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | AR-030056-A1 |
| titleOfInvention | PROCESS FOR THE PREPARATION OF PURIFIED CITALOPRAM |
| abstract | A process for the preparation of purified citalopram of formula 1 characterized by the elimination of desmethyl citalopram having formula 2 which comprises optionally subjecting a crude citalopram product containing the impurity of desmethyl citalopram to some initial purification and subsequently treating the product crude with an amide or a forming agent of the group of the amide type selected from the agents of formulas (a), (b) or (c) in which X is halogen or an O-COR 'group; Hal is halogen, Y is O or S, W is O, N or S and each of R, R ', R' 'and R' '' is independently selected from the group consisting of hydrogen, alkyl and aryl or aralkyl optionally substituted; The reaction mixture is then subjected to a wash with acid / base and / or crystallization or recrystallization of citalopram to remove the amides formed from the crude mixture of citalopram and optionally purified more deeply, the citalopram product produced is processed and / isolated in the form of base or pharmaceutically acceptable salt thereof. |
| priorityDate | 2000-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.