| abstract |
16alpha-substituted steroid compound having formula (1), where the dotted line ring is a fully saturated ring, a fully aromatic ring or a saturated ring with a double delta5-10 bond; R1 is C1-3 alkyl or C2-3 alkenyl, and each of these groups may be substituted with one or more halogens; R2 is C1-4 alkyl, C2-4 alkenyl, or methylene, and each of these groups may be substituted with one or more halogens; R3 is methyl or ethyl; or a prodrug thereof, whose compound can be used for a selective treatment for alpha estrogen receptors. |